Whole-Blood Gene Expression Profiles Correlate with Response to Immune Checkpoint Inhibitors in Patients with Metastatic Renal Cell Carcinoma

Whole-Blood Gene Expression Profiles Correlate with Response to Immune Checkpoint Inhibitors in Patients with Metastatic Renal Cell Carcinoma

In metastatic renal cell carcinoma (mRCC), the clinical response to immune checkpoint inhibitors (ICIs) is limited in a subset of patients and the need exists to identify non-invasive, blood-based, predictive biomarkers for responses. We performed RNA sequencing using whole-blood samples prospective...

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Bibliographic Details
Main Authors: Yoshiyuki Nagumo, Shuya Kandori, Takahiro Kojima, Kazuki Hamada, Satoshi Nitta, Ichiro Chihara, Masanobu Shiga, Hiromitsu Negoro, Bryan J. Mathis, Hiroyuki Nishiyama
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
whole-blood
gene expression
renal cell carcinoma
immune checkpoint inhibitor
response
Online Access:https://www.mdpi.com/2072-6694/14/24/6207

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