The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022
Currently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern inc...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33549-6 |
| _version_ | 1828108284548087808 |
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| author | Saranya Sridhar Roman M. Chicz William Warren Jim Tartaglia Stephen Savarino Sanjay Gurunathan Jean-Francois Toussaint |
| author_facet | Saranya Sridhar Roman M. Chicz William Warren Jim Tartaglia Stephen Savarino Sanjay Gurunathan Jean-Francois Toussaint |
| author_sort | Saranya Sridhar |
| collection | DOAJ |
| description | Currently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern including the most prevalent variant for the coming season. We here discuss recent preclinical and clinical data on COVID vaccine antigens that are potential candidates for an updated vaccine. |
| first_indexed | 2024-04-11T10:44:16Z |
| format | Article |
| id | doaj.art-613c37b00e15421f9f434ba2b8494c53 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T10:44:16Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-613c37b00e15421f9f434ba2b8494c532022-12-22T04:29:06ZengNature PortfolioNature Communications2041-17232022-10-011311310.1038/s41467-022-33549-6The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022Saranya Sridhar0Roman M. Chicz1William Warren2Jim Tartaglia3Stephen Savarino4Sanjay Gurunathan5Jean-Francois Toussaint6SanofiSanofiSanofiSanofiSanofiSanofiSanofiCurrently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern including the most prevalent variant for the coming season. We here discuss recent preclinical and clinical data on COVID vaccine antigens that are potential candidates for an updated vaccine.https://doi.org/10.1038/s41467-022-33549-6 |
| spellingShingle | Saranya Sridhar Roman M. Chicz William Warren Jim Tartaglia Stephen Savarino Sanjay Gurunathan Jean-Francois Toussaint The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 Nature Communications |
| title | The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 |
| title_full | The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 |
| title_fullStr | The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 |
| title_full_unstemmed | The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 |
| title_short | The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022 |
| title_sort | potential of beta variant containing covid booster vaccines for chasing omicron in 2022 |
| url | https://doi.org/10.1038/s41467-022-33549-6 |
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