Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”

Abstract The goal of this study was to reproduce and evaluate the reliability of the network meta-analysis performed in the article “The best drug supplement for obesity treatment: A systematic review and network meta-analysis” by Salari et al. In recent years, it has become more common to employ ne...

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Main Authors: Xiaoxin Yu, Patrice L. Capers, Roger S. Zoh, David B. Allison
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-023-01134-6
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author Xiaoxin Yu
Patrice L. Capers
Roger S. Zoh
David B. Allison
author_facet Xiaoxin Yu
Patrice L. Capers
Roger S. Zoh
David B. Allison
author_sort Xiaoxin Yu
collection DOAJ
description Abstract The goal of this study was to reproduce and evaluate the reliability of the network meta-analysis performed in the article “The best drug supplement for obesity treatment: A systematic review and network meta-analysis” by Salari et al. In recent years, it has become more common to employ network meta-analysis to assess the relative efficacy of treatments often used in clinical practice. To duplicate Salari et al.‘s research, we pulled data directly from the original trials and used Cohen’s D to determine the effect size for each treatment. We reanalyzed the data since we discovered significant differences between the data we retrieved and the data given by Salari et al. We present new effect size estimates for each therapy and conclude that the prior findings were somewhat erroneous. Our findings highlight the importance of ensuring the accuracy of network meta-analyses to determine the quality and strength of existing evidence.
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spelling doaj.art-61405b0e393a45d5babca62416b27aa52023-07-23T11:21:19ZengBMCDiabetology & Metabolic Syndrome1758-59962023-07-011511810.1186/s13098-023-01134-6Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”Xiaoxin Yu0Patrice L. Capers1Roger S. Zoh2David B. Allison3Department of Epidemiology and Biostatistics, School of Public Health, Indiana University – BloomingtonDepartment of Biology, Swain Family School of Science and Mathematics, The Citadel – CharlestonDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University – BloomingtonDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University – BloomingtonAbstract The goal of this study was to reproduce and evaluate the reliability of the network meta-analysis performed in the article “The best drug supplement for obesity treatment: A systematic review and network meta-analysis” by Salari et al. In recent years, it has become more common to employ network meta-analysis to assess the relative efficacy of treatments often used in clinical practice. To duplicate Salari et al.‘s research, we pulled data directly from the original trials and used Cohen’s D to determine the effect size for each treatment. We reanalyzed the data since we discovered significant differences between the data we retrieved and the data given by Salari et al. We present new effect size estimates for each therapy and conclude that the prior findings were somewhat erroneous. Our findings highlight the importance of ensuring the accuracy of network meta-analyses to determine the quality and strength of existing evidence.https://doi.org/10.1186/s13098-023-01134-6Network meta-analysisDrug supplementObesity treatmentRigorReproducibility
spellingShingle Xiaoxin Yu
Patrice L. Capers
Roger S. Zoh
David B. Allison
Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
Diabetology & Metabolic Syndrome
Network meta-analysis
Drug supplement
Obesity treatment
Rigor
Reproducibility
title Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
title_full Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
title_fullStr Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
title_full_unstemmed Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
title_short Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
title_sort correcting calculation and data errors reveals that the original conclusions were incorrect in the best drug supplement for obesity treatment a systematic review and network meta analysis
topic Network meta-analysis
Drug supplement
Obesity treatment
Rigor
Reproducibility
url https://doi.org/10.1186/s13098-023-01134-6
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