Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells
The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of t...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2014-09-01
|
| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/20/9/14-0257_article |
| _version_ | 1818284844980895744 |
|---|---|
| author | Jian Yang Ting Zhang Li Guo Yongfeng Hu Jinlin Li Haoxiang Su Yan Xiao Xianwen Ren Jie Dong Lilian Sun |
| author_facet | Jian Yang Ting Zhang Li Guo Yongfeng Hu Jinlin Li Haoxiang Su Yan Xiao Xianwen Ren Jie Dong Lilian Sun |
| author_sort | Jian Yang |
| collection | DOAJ |
| description | The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of this influenza virus. |
| first_indexed | 2024-12-13T00:59:16Z |
| format | Article |
| id | doaj.art-6141bd8217b84e8a860ac6942ea7f20a |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-13T00:59:16Z |
| publishDate | 2014-09-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-6141bd8217b84e8a860ac6942ea7f20a2022-12-22T00:04:44ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-09-012091541154310.3201/eid2009.140257Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK CellsJian YangTing ZhangLi GuoYongfeng HuJinlin LiHaoxiang SuYan XiaoXianwen RenJie DongLilian SunThe recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of this influenza virus.https://wwwnc.cdc.gov/eid/article/20/9/14-0257_articleinfluenza A virusmutationgenomeavian-originantiviral drug resistanceviruses |
| spellingShingle | Jian Yang Ting Zhang Li Guo Yongfeng Hu Jinlin Li Haoxiang Su Yan Xiao Xianwen Ren Jie Dong Lilian Sun Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells Emerging Infectious Diseases influenza A virus mutation genome avian-origin antiviral drug resistance viruses |
| title | Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells |
| title_full | Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells |
| title_fullStr | Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells |
| title_full_unstemmed | Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells |
| title_short | Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells |
| title_sort | mutations of novel influenza a h10n8 virus in chicken eggs and mdck cells |
| topic | influenza A virus mutation genome avian-origin antiviral drug resistance viruses |
| url | https://wwwnc.cdc.gov/eid/article/20/9/14-0257_article |
| work_keys_str_mv | AT jianyang mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT tingzhang mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT liguo mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT yongfenghu mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT jinlinli mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT haoxiangsu mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT yanxiao mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT xianwenren mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT jiedong mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells AT liliansun mutationsofnovelinfluenzaah10n8virusinchickeneggsandmdckcells |