Three-Component Synthesis of Polysubstituted Homoproline Analogs
Tetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding carbon positions of the bicyclic pyrrolidine...
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MDPI AG
2005-08-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/10/7/755/ |
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author | V. Irkha K. Kudryavtsev |
author_facet | V. Irkha K. Kudryavtsev |
author_sort | V. Irkha |
collection | DOAJ |
description | Tetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding carbon positions of the bicyclic pyrrolidine ring could be isolated ona preparative scale. |
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format | Article |
id | doaj.art-61453cdad2554afdae1cb8933df1d6b4 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-12-22T07:47:07Z |
publishDate | 2005-08-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-61453cdad2554afdae1cb8933df1d6b42022-12-21T18:33:36ZengMDPI AGMolecules1420-30492005-08-0110775576110.3390/10070755Three-Component Synthesis of Polysubstituted Homoproline AnalogsV. IrkhaK. KudryavtsevTetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding carbon positions of the bicyclic pyrrolidine ring could be isolated ona preparative scale.http://www.mdpi.com/1420-3049/10/7/755/Multicomponent reactions13-dipolar cycloadditionhomoproline. |
spellingShingle | V. Irkha K. Kudryavtsev Three-Component Synthesis of Polysubstituted Homoproline Analogs Molecules Multicomponent reactions 1 3-dipolar cycloaddition homoproline. |
title | Three-Component Synthesis of Polysubstituted Homoproline Analogs |
title_full | Three-Component Synthesis of Polysubstituted Homoproline Analogs |
title_fullStr | Three-Component Synthesis of Polysubstituted Homoproline Analogs |
title_full_unstemmed | Three-Component Synthesis of Polysubstituted Homoproline Analogs |
title_short | Three-Component Synthesis of Polysubstituted Homoproline Analogs |
title_sort | three component synthesis of polysubstituted homoproline analogs |
topic | Multicomponent reactions 1 3-dipolar cycloaddition homoproline. |
url | http://www.mdpi.com/1420-3049/10/7/755/ |
work_keys_str_mv | AT virkha threecomponentsynthesisofpolysubstitutedhomoprolineanalogs AT kkudryavtsev threecomponentsynthesisofpolysubstitutedhomoprolineanalogs |