Surface Functionalities of Polymers for Biomaterial Applications
Changes of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
|
Series: | Polymers |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4360/14/12/2307 |
_version_ | 1797483067797929984 |
---|---|
author | Mioara Drobota Stefan Ursache Magdalena Aflori |
author_facet | Mioara Drobota Stefan Ursache Magdalena Aflori |
author_sort | Mioara Drobota |
collection | DOAJ |
description | Changes of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with improved functionality. Furthermore, a variety of physical and chemical techniques have been utilized to improve biomaterial functionality, particularly at the material interface. At the interface level, the interactions between materials and cells are described. The importance of surface features in cell function is then examined, with new strategies for surface modification being highlighted in detail. |
first_indexed | 2024-03-09T22:42:32Z |
format | Article |
id | doaj.art-6145d644151a44b4887da8a22c8481a5 |
institution | Directory Open Access Journal |
issn | 2073-4360 |
language | English |
last_indexed | 2024-03-09T22:42:32Z |
publishDate | 2022-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Polymers |
spelling | doaj.art-6145d644151a44b4887da8a22c8481a52023-11-23T18:35:47ZengMDPI AGPolymers2073-43602022-06-011412230710.3390/polym14122307Surface Functionalities of Polymers for Biomaterial ApplicationsMioara Drobota0Stefan Ursache1Magdalena Aflori2“Petru Poni” Institute of Macromolecular Chemistry, 41A Aleea Gr. Ghica Voda, 700487 Iasi, RomaniaInnovative Green Power, No. 5 Iancu Bacalu Street, 700029 Iasi, Romania“Petru Poni” Institute of Macromolecular Chemistry, 41A Aleea Gr. Ghica Voda, 700487 Iasi, RomaniaChanges of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with improved functionality. Furthermore, a variety of physical and chemical techniques have been utilized to improve biomaterial functionality, particularly at the material interface. At the interface level, the interactions between materials and cells are described. The importance of surface features in cell function is then examined, with new strategies for surface modification being highlighted in detail.https://www.mdpi.com/2073-4360/14/12/2307biomaterialsurface functionalitiespolymerscell–interface interactionantimicrobial |
spellingShingle | Mioara Drobota Stefan Ursache Magdalena Aflori Surface Functionalities of Polymers for Biomaterial Applications Polymers biomaterial surface functionalities polymers cell–interface interaction antimicrobial |
title | Surface Functionalities of Polymers for Biomaterial Applications |
title_full | Surface Functionalities of Polymers for Biomaterial Applications |
title_fullStr | Surface Functionalities of Polymers for Biomaterial Applications |
title_full_unstemmed | Surface Functionalities of Polymers for Biomaterial Applications |
title_short | Surface Functionalities of Polymers for Biomaterial Applications |
title_sort | surface functionalities of polymers for biomaterial applications |
topic | biomaterial surface functionalities polymers cell–interface interaction antimicrobial |
url | https://www.mdpi.com/2073-4360/14/12/2307 |
work_keys_str_mv | AT mioaradrobota surfacefunctionalitiesofpolymersforbiomaterialapplications AT stefanursache surfacefunctionalitiesofpolymersforbiomaterialapplications AT magdalenaaflori surfacefunctionalitiesofpolymersforbiomaterialapplications |