Surface Functionalities of Polymers for Biomaterial Applications

Changes of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with...

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Main Authors: Mioara Drobota, Stefan Ursache, Magdalena Aflori
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/12/2307
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author Mioara Drobota
Stefan Ursache
Magdalena Aflori
author_facet Mioara Drobota
Stefan Ursache
Magdalena Aflori
author_sort Mioara Drobota
collection DOAJ
description Changes of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with improved functionality. Furthermore, a variety of physical and chemical techniques have been utilized to improve biomaterial functionality, particularly at the material interface. At the interface level, the interactions between materials and cells are described. The importance of surface features in cell function is then examined, with new strategies for surface modification being highlighted in detail.
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spelling doaj.art-6145d644151a44b4887da8a22c8481a52023-11-23T18:35:47ZengMDPI AGPolymers2073-43602022-06-011412230710.3390/polym14122307Surface Functionalities of Polymers for Biomaterial ApplicationsMioara Drobota0Stefan Ursache1Magdalena Aflori2“Petru Poni” Institute of Macromolecular Chemistry, 41A Aleea Gr. Ghica Voda, 700487 Iasi, RomaniaInnovative Green Power, No. 5 Iancu Bacalu Street, 700029 Iasi, Romania“Petru Poni” Institute of Macromolecular Chemistry, 41A Aleea Gr. Ghica Voda, 700487 Iasi, RomaniaChanges of a material biointerface allow for specialized cell signaling and diverse biological responses. Biomaterials incorporating immobilized bioactive ligands have been widely introduced and used for tissue engineering and regenerative medicine applications in order to develop biomaterials with improved functionality. Furthermore, a variety of physical and chemical techniques have been utilized to improve biomaterial functionality, particularly at the material interface. At the interface level, the interactions between materials and cells are described. The importance of surface features in cell function is then examined, with new strategies for surface modification being highlighted in detail.https://www.mdpi.com/2073-4360/14/12/2307biomaterialsurface functionalitiespolymerscell–interface interactionantimicrobial
spellingShingle Mioara Drobota
Stefan Ursache
Magdalena Aflori
Surface Functionalities of Polymers for Biomaterial Applications
Polymers
biomaterial
surface functionalities
polymers
cell–interface interaction
antimicrobial
title Surface Functionalities of Polymers for Biomaterial Applications
title_full Surface Functionalities of Polymers for Biomaterial Applications
title_fullStr Surface Functionalities of Polymers for Biomaterial Applications
title_full_unstemmed Surface Functionalities of Polymers for Biomaterial Applications
title_short Surface Functionalities of Polymers for Biomaterial Applications
title_sort surface functionalities of polymers for biomaterial applications
topic biomaterial
surface functionalities
polymers
cell–interface interaction
antimicrobial
url https://www.mdpi.com/2073-4360/14/12/2307
work_keys_str_mv AT mioaradrobota surfacefunctionalitiesofpolymersforbiomaterialapplications
AT stefanursache surfacefunctionalitiesofpolymersforbiomaterialapplications
AT magdalenaaflori surfacefunctionalitiesofpolymersforbiomaterialapplications