The mTOR–Autophagy Axis and the Control of Metabolism
The mechanistic target of rapamycin (mTOR), master regulator of cellular metabolism, exists in two distinct complexes: mTOR complex 1 and mTOR complex 2 (mTORC1 and 2). MTORC1 is a master switch for most energetically onerous processes in the cell, driving cell growth and building cellular biomass i...
Main Authors: | Nerea Deleyto-Seldas, Alejo Efeyan |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.655731/full |
Similar Items
-
mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy
by: Sanjar Batirovich Madrakhimov, et al.
Published: (2021-02-01) -
Regulation of Autophagy in Chick Skeletal Muscle: Effect of mTOR Inhibition
by: Kazuki Nakashima, et al.
Published: (2020-01-01) -
Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes
by: Guo Yan Wang, et al.
Published: (2023-12-01) -
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome
by: Na Xiao, et al.
Published: (2022-06-01) -
Alpha‐lipoic acid inhibits lung cancer growth via mTOR‐mediated autophagy inhibition
by: Peipei Peng, et al.
Published: (2020-04-01)