Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications

Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications

The six transcriptomic immune subtypes (ISs) (C1 - C6) were reported to have complex and different interplay between TME and cancer cells in TCGA (The Cancer Genome Atlas) pan-cancer cohort. Our study specifically explored how the consequence of interplay determines the prognosis and the response to...

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Bibliographic Details
Main Authors: Feng Wang, Xuan Gao, Peiyuan Wang, Hao He, Peng Chen, Zhentian Liu, Yujie Chen, Hang Zhou, Weijie Chen, Xin Yi, Xuefeng Xia, Shuoyan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
lung adenocarcinoma
prognostic signature
TME
immune subtypes (ISs)
precision medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.877896/full

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