Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms

The study was conducted to determine the neurohormonal mechanisms that underlie the clinical features of puberty onset in children born to parents exposed to low-dose irradiation. Hormonal homeostasis is assessed according to the data of immune-enzyme, radioimmune, and fluorometric methods. Statisti...

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Main Authors: O.I. Plekhova, S.O. Levenets, G.O. Borysko, T.P. Kostenko, V.L. Kashina-Yarmak, V.V. Perevozchykov
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2014-04-01
Series:Zdorovʹe Rebenka
Subjects:
Online Access:http://childshealth.zaslavsky.com.ua/article/view/76001
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author O.I. Plekhova
S.O. Levenets
G.O. Borysko
T.P. Kostenko
V.L. Kashina-Yarmak
V.V. Perevozchykov
author_facet O.I. Plekhova
S.O. Levenets
G.O. Borysko
T.P. Kostenko
V.L. Kashina-Yarmak
V.V. Perevozchykov
author_sort O.I. Plekhova
collection DOAJ
description The study was conducted to determine the neurohormonal mechanisms that underlie the clinical features of puberty onset in children born to parents exposed to low-dose irradiation. Hormonal homeostasis is assessed according to the data of immune-enzyme, radioimmune, and fluorometric methods. Statistical analysis of the data was carried out by means of the application package Excel and Statgrafics-5, SPSS 17.0. It has been established that the earlier puberty onset is caused by accelerated stimulation of pituitary-gonadal system due to activation of central mechanisms of pituitary gonadotrophic function regulation and eary reversal of melatonin blockage of this system. Reasonable basis has been suggested for careful clinical supervision over development of the reproductive system of the children from families with burdened radiation history.
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spelling doaj.art-614a37464c704c5eae013636085e08cc2022-12-21T19:42:30ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682014-04-0193.54616410.22141/2224-0551.3.54.2014.7600176001Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal MechanismsO.I. Plekhova0S.O. Levenets1G.O. Borysko2T.P. Kostenko3V.L. Kashina-Yarmak4V.V. Perevozchykov5State Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivThe study was conducted to determine the neurohormonal mechanisms that underlie the clinical features of puberty onset in children born to parents exposed to low-dose irradiation. Hormonal homeostasis is assessed according to the data of immune-enzyme, radioimmune, and fluorometric methods. Statistical analysis of the data was carried out by means of the application package Excel and Statgrafics-5, SPSS 17.0. It has been established that the earlier puberty onset is caused by accelerated stimulation of pituitary-gonadal system due to activation of central mechanisms of pituitary gonadotrophic function regulation and eary reversal of melatonin blockage of this system. Reasonable basis has been suggested for careful clinical supervision over development of the reproductive system of the children from families with burdened radiation history.http://childshealth.zaslavsky.com.ua/article/view/76001pubertyhormonesradiation
spellingShingle O.I. Plekhova
S.O. Levenets
G.O. Borysko
T.P. Kostenko
V.L. Kashina-Yarmak
V.V. Perevozchykov
Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
Zdorovʹe Rebenka
puberty
hormones
radiation
title Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
title_full Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
title_fullStr Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
title_full_unstemmed Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
title_short Features of Puberty Onset in Children Born to Fathers with Burdened Radiation Anamnesis. Neurohormonal Mechanisms
title_sort features of puberty onset in children born to fathers with burdened radiation anamnesis neurohormonal mechanisms
topic puberty
hormones
radiation
url http://childshealth.zaslavsky.com.ua/article/view/76001
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