Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology

Cerebrovascular events are increasingly recognized as a complication of SARS-CoV-2 infections. They can be due to hypercoagulability, vasculopathy, cardiac involvement in the infection, or autonomic dysfunction. However, establishing a causal relationship between cerebrovascular events and viral inf...

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Main Authors: Josef Finsterer, Fulvio A. Scorza, Antonio-Carlos G. de Almeida
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Brain Hemorrhages
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589238X22000596
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author Josef Finsterer
Fulvio A. Scorza
Antonio-Carlos G. de Almeida
author_facet Josef Finsterer
Fulvio A. Scorza
Antonio-Carlos G. de Almeida
author_sort Josef Finsterer
collection DOAJ
description Cerebrovascular events are increasingly recognized as a complication of SARS-CoV-2 infections. They can be due to hypercoagulability, vasculopathy, cardiac involvement in the infection, or autonomic dysfunction. However, establishing a causal relationship between cerebrovascular events and viral infection is not always easy and requires thorough investigation and documentation of a close temporal relationship between SARS-CoV-2 infection and the onset of cerebral impairment. Establishing a causal relationship between SARS-CoV-2 infection and cerebrovascular events is desirable as it can guide therapeutic management and determine the outcome.
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spelling doaj.art-614c75afca1d4c90bc37839a37397eba2023-09-09T04:56:08ZengKeAi Communications Co., Ltd.Brain Hemorrhages2589-238X2023-09-0143174175Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiologyJosef Finsterer0Fulvio A. Scorza1Antonio-Carlos G. de Almeida2Neurology & Neurophysiology Center, Vienna, Austria; Corresponding author at: Postfach 20, 1180 Vienna, Austria.Disciplina de Neurociência. Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM). São Paulo, BrazilCentro de Neurociências e Saúde da Mulher “Professor Geraldo Rodrigues de Lima.” Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP). São Paulo, BrazilCerebrovascular events are increasingly recognized as a complication of SARS-CoV-2 infections. They can be due to hypercoagulability, vasculopathy, cardiac involvement in the infection, or autonomic dysfunction. However, establishing a causal relationship between cerebrovascular events and viral infection is not always easy and requires thorough investigation and documentation of a close temporal relationship between SARS-CoV-2 infection and the onset of cerebral impairment. Establishing a causal relationship between SARS-CoV-2 infection and cerebrovascular events is desirable as it can guide therapeutic management and determine the outcome.http://www.sciencedirect.com/science/article/pii/S2589238X22000596SARS-CoV-2COVID-19StrokeBleedingOutcome
spellingShingle Josef Finsterer
Fulvio A. Scorza
Antonio-Carlos G. de Almeida
Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
Brain Hemorrhages
SARS-CoV-2
COVID-19
Stroke
Bleeding
Outcome
title Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
title_full Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
title_fullStr Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
title_full_unstemmed Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
title_short Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology
title_sort establishing causality between sars cov 2 and stroke bleeding requires a temporal relationship and plausible pathophysiology
topic SARS-CoV-2
COVID-19
Stroke
Bleeding
Outcome
url http://www.sciencedirect.com/science/article/pii/S2589238X22000596
work_keys_str_mv AT joseffinsterer establishingcausalitybetweensarscov2andstrokebleedingrequiresatemporalrelationshipandplausiblepathophysiology
AT fulvioascorza establishingcausalitybetweensarscov2andstrokebleedingrequiresatemporalrelationshipandplausiblepathophysiology
AT antoniocarlosgdealmeida establishingcausalitybetweensarscov2andstrokebleedingrequiresatemporalrelationshipandplausiblepathophysiology