Research Progress on the Flexibility of an Implantable Neural Microelectrode

Neural microelectrode is the important bridge of information exchange between the human body and machines. By recording and transmitting nerve signals with electrodes, people can control the external machines. At the same time, using electrodes to electrically stimulate nerve tissue, people with lon...

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Main Authors: Huiqing Zhao, Ruping Liu, Huiling Zhang, Peng Cao, Zilong Liu, Ye Li
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/13/3/386
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author Huiqing Zhao
Ruping Liu
Huiling Zhang
Peng Cao
Zilong Liu
Ye Li
author_facet Huiqing Zhao
Ruping Liu
Huiling Zhang
Peng Cao
Zilong Liu
Ye Li
author_sort Huiqing Zhao
collection DOAJ
description Neural microelectrode is the important bridge of information exchange between the human body and machines. By recording and transmitting nerve signals with electrodes, people can control the external machines. At the same time, using electrodes to electrically stimulate nerve tissue, people with long-term brain diseases will be safely and reliably treated. Young’s modulus of the traditional rigid electrode probe is not matched well with that of biological tissue, and tissue immune rejection is easy to generate, resulting in the electrode not being able to achieve long-term safety and reliable working. In recent years, the choice of flexible materials and design of electrode structures can achieve modulus matching between electrode and biological tissue, and tissue damage is decreased. This review discusses nerve microelectrodes based on flexible electrode materials and substrate materials. Simultaneously, different structural designs of neural microelectrodes are reviewed. However, flexible electrode probes are difficult to implant into the brain. Only with the aid of certain auxiliary devices, can the implant be safe and reliable. The implantation method of the nerve microelectrode is also reviewed.
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spelling doaj.art-614d267ed6004a6f8f7ff41f5bd0f2fd2023-11-30T21:33:26ZengMDPI AGMicromachines2072-666X2022-02-0113338610.3390/mi13030386Research Progress on the Flexibility of an Implantable Neural MicroelectrodeHuiqing Zhao0Ruping Liu1Huiling Zhang2Peng Cao3Zilong Liu4Ye Li5Beijing Institute of Graphic Communication, Beijing 102600, ChinaBeijing Institute of Graphic Communication, Beijing 102600, ChinaBeijing Institute of Graphic Communication, Beijing 102600, ChinaBeijing Institute of Graphic Communication, Beijing 102600, ChinaDivision of Optics, National Institute of Metrology, Beijing 100029, ChinaBeijing Institute of Graphic Communication, Beijing 102600, ChinaNeural microelectrode is the important bridge of information exchange between the human body and machines. By recording and transmitting nerve signals with electrodes, people can control the external machines. At the same time, using electrodes to electrically stimulate nerve tissue, people with long-term brain diseases will be safely and reliably treated. Young’s modulus of the traditional rigid electrode probe is not matched well with that of biological tissue, and tissue immune rejection is easy to generate, resulting in the electrode not being able to achieve long-term safety and reliable working. In recent years, the choice of flexible materials and design of electrode structures can achieve modulus matching between electrode and biological tissue, and tissue damage is decreased. This review discusses nerve microelectrodes based on flexible electrode materials and substrate materials. Simultaneously, different structural designs of neural microelectrodes are reviewed. However, flexible electrode probes are difficult to implant into the brain. Only with the aid of certain auxiliary devices, can the implant be safe and reliable. The implantation method of the nerve microelectrode is also reviewed.https://www.mdpi.com/2072-666X/13/3/386neural microelectrodeflexible materialselectrode structureelectrode implantation method
spellingShingle Huiqing Zhao
Ruping Liu
Huiling Zhang
Peng Cao
Zilong Liu
Ye Li
Research Progress on the Flexibility of an Implantable Neural Microelectrode
Micromachines
neural microelectrode
flexible materials
electrode structure
electrode implantation method
title Research Progress on the Flexibility of an Implantable Neural Microelectrode
title_full Research Progress on the Flexibility of an Implantable Neural Microelectrode
title_fullStr Research Progress on the Flexibility of an Implantable Neural Microelectrode
title_full_unstemmed Research Progress on the Flexibility of an Implantable Neural Microelectrode
title_short Research Progress on the Flexibility of an Implantable Neural Microelectrode
title_sort research progress on the flexibility of an implantable neural microelectrode
topic neural microelectrode
flexible materials
electrode structure
electrode implantation method
url https://www.mdpi.com/2072-666X/13/3/386
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