A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
Abstract Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. Case Presentation In this report...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-023-02389-w |
| _version_ | 1797451541955739648 |
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| author | Parviz Mardani Hooman Kamran Rezvan Ghaderpanah Bita Geramizadeh Damoun Fouladi Reza Shahriarirad Armin Amirian |
| author_facet | Parviz Mardani Hooman Kamran Rezvan Ghaderpanah Bita Geramizadeh Damoun Fouladi Reza Shahriarirad Armin Amirian |
| author_sort | Parviz Mardani |
| collection | DOAJ |
| description | Abstract Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. Case Presentation In this report, we presented a 24-year-old patient with dyspnea, chest pain, nausea, and anorexia. A computed tomography scan revealed a giant, right-sided mass measuring about 190 × 150 × 140 mm. Chemotherapy was initiated for the patient, followed by thoracotomy. Histopathological evaluation revealed the nature of the mass to be an immature mediastinal teratoma. Conclusion the incidence of immature mediastinal teratoma is uncommon, and due to its rarity, the diagnosis needs more profound evaluation studies such as radiological and pathological assessments. Immature teratomas are optimally treated by a combination of chemotherapy and complete resection. |
| first_indexed | 2024-03-09T14:56:07Z |
| format | Article |
| id | doaj.art-614eee69e61b46a8bfd4983924e56730 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-03-09T14:56:07Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-614eee69e61b46a8bfd4983924e567302023-11-26T14:12:03ZengBMCJournal of Cardiothoracic Surgery1749-80902023-10-011811710.1186/s13019-023-02389-wA massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case reportParviz Mardani0Hooman Kamran1Rezvan Ghaderpanah2Bita Geramizadeh3Damoun Fouladi4Reza Shahriarirad5Armin Amirian6Thoracic and Vascular Surgery Research Center, Shiraz University of Medical ScienceThoracic and Vascular Surgery Research Center, Shiraz University of Medical ScienceStudents Research Committee, School of Medicine, Shiraz University of Medical SciencesShiraz Transplant Research Center (STRC), Shiraz University of Medical SciencesThoracic and Vascular Surgery Research Center, Shiraz University of Medical ScienceThoracic and Vascular Surgery Research Center, Shiraz University of Medical ScienceThoracic and Vascular Surgery Research Center, Shiraz University of Medical ScienceAbstract Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. Case Presentation In this report, we presented a 24-year-old patient with dyspnea, chest pain, nausea, and anorexia. A computed tomography scan revealed a giant, right-sided mass measuring about 190 × 150 × 140 mm. Chemotherapy was initiated for the patient, followed by thoracotomy. Histopathological evaluation revealed the nature of the mass to be an immature mediastinal teratoma. Conclusion the incidence of immature mediastinal teratoma is uncommon, and due to its rarity, the diagnosis needs more profound evaluation studies such as radiological and pathological assessments. Immature teratomas are optimally treated by a combination of chemotherapy and complete resection.https://doi.org/10.1186/s13019-023-02389-wTeratomaThoracotomySurgeryChemotherapyNeoplasms, Germ Cell and EmbryonalMediastinal Neoplasms |
| spellingShingle | Parviz Mardani Hooman Kamran Rezvan Ghaderpanah Bita Geramizadeh Damoun Fouladi Reza Shahriarirad Armin Amirian A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report Journal of Cardiothoracic Surgery Teratoma Thoracotomy Surgery Chemotherapy Neoplasms, Germ Cell and Embryonal Mediastinal Neoplasms |
| title | A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report |
| title_full | A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report |
| title_fullStr | A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report |
| title_full_unstemmed | A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report |
| title_short | A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report |
| title_sort | massive immature mediastinal teratoma treated with chemotherapy and surgical resection a case report |
| topic | Teratoma Thoracotomy Surgery Chemotherapy Neoplasms, Germ Cell and Embryonal Mediastinal Neoplasms |
| url | https://doi.org/10.1186/s13019-023-02389-w |
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