Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer

Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer

The Transforming Growth Factor-β (TGF-β) signaling pathway has a well-documented, context-dependent role in breast cancer development. In normal and premalignant cells, it acts as a tumor suppressor. By contrast, during the malignant phases of breast cancer progression, the TGF-&am...

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Bibliographic Details
Main Authors:	Sudha Suriyamurthy, David Baker, Peter ten Dijke, Prasanna Vasudevan Iyengar
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	Cancers
Subjects:	breast cancer epigenetics epithelial to mesenchymal transition signal transduction SMAD TGF-β
Online Access:	https://www.mdpi.com/2072-6694/11/5/726

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