Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units
<i>Background and Objectives</i>: Phytotherapeutically, various herbal remedies, such as St. John’s wort oil, have been introduced as wound care options. Recently, Neem oil has been considered a herbal option for the management of superficial wounds. Wound care is a complex process that...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/3/467 |
| _version_ | 1827748823254958080 |
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| author | Samet Özdemir Saber Yari Bostanabad Ayhan Parmaksız Halil Can Canatan |
| author_facet | Samet Özdemir Saber Yari Bostanabad Ayhan Parmaksız Halil Can Canatan |
| author_sort | Samet Özdemir |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Phytotherapeutically, various herbal remedies, such as St. John’s wort oil, have been introduced as wound care options. Recently, Neem oil has been considered a herbal option for the management of superficial wounds. Wound care is a complex process that involves several factors including the patient, caregiver, and medications. Herbal combinations could be an alternative to the chemical counterparts in the wound care area. This report includes an investigation of the possible supportive impacts of the St. John’s wort and Neem oil containing ointment (W Cura G Plus <sup>®</sup>) in the management of pressure ulcers (PUs) in three intensive care unit (ICU) patients. <i>Materials and Methods</i>: The ointment was administered to individuals once daily for 42 consecutive days. The status of individuals was macroscopically monitored by measuring the PU area and histopathological assessment of the tissue sections taken on the first and last days of wound treatment. <i>Results</i>: The outcomes of the macroscopic and histopathological techniques exhibited that St. John’s wort and Neem oil containing ointment provided a remarkable supportive impact on the patients that suffered from PUs in the ICUs. <i>Conclusions</i>: The combination of St. John’s wort and Neem oil could be suggested as an efficient active phytoconstituent for the management of PUs. The herbal ointments may be suggested as an alternative for the patients that have PUs in the ICUs. |
| first_indexed | 2024-03-11T06:12:18Z |
| format | Article |
| id | doaj.art-6150f12565e342dd8ce73c1e8b802db6 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T06:12:18Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-6150f12565e342dd8ce73c1e8b802db62023-11-17T12:31:03ZengMDPI AGMedicina1010-660X1648-91442023-02-0159346710.3390/medicina59030467Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care UnitsSamet Özdemir0Saber Yari Bostanabad1Ayhan Parmaksız2Halil Can Canatan3Department of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34015, TurkeyDepartment of Pharmacology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34015, TurkeyDepartment of Biostatistics, Faculty of Medicine, Istanbul Health and Technology University, Istanbul 34015, TurkeyIntensive Care Unit, Department of Anesthesiology and Reanimation, Istanbul Special Güngören Hospital, Istanbul 34164, Turkey<i>Background and Objectives</i>: Phytotherapeutically, various herbal remedies, such as St. John’s wort oil, have been introduced as wound care options. Recently, Neem oil has been considered a herbal option for the management of superficial wounds. Wound care is a complex process that involves several factors including the patient, caregiver, and medications. Herbal combinations could be an alternative to the chemical counterparts in the wound care area. This report includes an investigation of the possible supportive impacts of the St. John’s wort and Neem oil containing ointment (W Cura G Plus <sup>®</sup>) in the management of pressure ulcers (PUs) in three intensive care unit (ICU) patients. <i>Materials and Methods</i>: The ointment was administered to individuals once daily for 42 consecutive days. The status of individuals was macroscopically monitored by measuring the PU area and histopathological assessment of the tissue sections taken on the first and last days of wound treatment. <i>Results</i>: The outcomes of the macroscopic and histopathological techniques exhibited that St. John’s wort and Neem oil containing ointment provided a remarkable supportive impact on the patients that suffered from PUs in the ICUs. <i>Conclusions</i>: The combination of St. John’s wort and Neem oil could be suggested as an efficient active phytoconstituent for the management of PUs. The herbal ointments may be suggested as an alternative for the patients that have PUs in the ICUs.https://www.mdpi.com/1648-9144/59/3/467St. John’s wort oilNeem oilpressure ulcersherbal ointment |
| spellingShingle | Samet Özdemir Saber Yari Bostanabad Ayhan Parmaksız Halil Can Canatan Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units Medicina St. John’s wort oil Neem oil pressure ulcers herbal ointment |
| title | Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units |
| title_full | Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units |
| title_fullStr | Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units |
| title_full_unstemmed | Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units |
| title_short | Combination of St. John’s Wort Oil and Neem Oil in Pharmaceuticals: An Effective Treatment Option for Pressure Ulcers in Intensive Care Units |
| title_sort | combination of st john s wort oil and neem oil in pharmaceuticals an effective treatment option for pressure ulcers in intensive care units |
| topic | St. John’s wort oil Neem oil pressure ulcers herbal ointment |
| url | https://www.mdpi.com/1648-9144/59/3/467 |
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