Structures of the eukaryotic ribosome and its translational states in situ
The translational states of eukaryotic ribosomes have so far been only investigated in vitro. Here, authors obtained the 3.8 Å in situ 80S ribosome structure, the distribution of translational states and unique arrangement of rRNA expansion segments.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34997-w |
| _version_ | 1811190473625174016 |
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| author | Patrick C. Hoffmann Jan Philipp Kreysing Iskander Khusainov Maarten W. Tuijtel Sonja Welsch Martin Beck |
| author_facet | Patrick C. Hoffmann Jan Philipp Kreysing Iskander Khusainov Maarten W. Tuijtel Sonja Welsch Martin Beck |
| author_sort | Patrick C. Hoffmann |
| collection | DOAJ |
| description | The translational states of eukaryotic ribosomes have so far been only investigated in vitro. Here, authors obtained the 3.8 Å in situ 80S ribosome structure, the distribution of translational states and unique arrangement of rRNA expansion segments. |
| first_indexed | 2024-04-11T14:50:39Z |
| format | Article |
| id | doaj.art-61565a935e9f4e16a4c80b3f1fb12c5e |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T14:50:39Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-61565a935e9f4e16a4c80b3f1fb12c5e2022-12-22T04:17:27ZengNature PortfolioNature Communications2041-17232022-12-011311910.1038/s41467-022-34997-wStructures of the eukaryotic ribosome and its translational states in situPatrick C. Hoffmann0Jan Philipp Kreysing1Iskander Khusainov2Maarten W. Tuijtel3Sonja Welsch4Martin Beck5Department of Molecular Sociology, Max Planck Institute of BiophysicsDepartment of Molecular Sociology, Max Planck Institute of BiophysicsDepartment of Molecular Sociology, Max Planck Institute of BiophysicsDepartment of Molecular Sociology, Max Planck Institute of BiophysicsCentral Electron Microscopy Facility, Max Planck Institute of BiophysicsDepartment of Molecular Sociology, Max Planck Institute of BiophysicsThe translational states of eukaryotic ribosomes have so far been only investigated in vitro. Here, authors obtained the 3.8 Å in situ 80S ribosome structure, the distribution of translational states and unique arrangement of rRNA expansion segments.https://doi.org/10.1038/s41467-022-34997-w |
| spellingShingle | Patrick C. Hoffmann Jan Philipp Kreysing Iskander Khusainov Maarten W. Tuijtel Sonja Welsch Martin Beck Structures of the eukaryotic ribosome and its translational states in situ Nature Communications |
| title | Structures of the eukaryotic ribosome and its translational states in situ |
| title_full | Structures of the eukaryotic ribosome and its translational states in situ |
| title_fullStr | Structures of the eukaryotic ribosome and its translational states in situ |
| title_full_unstemmed | Structures of the eukaryotic ribosome and its translational states in situ |
| title_short | Structures of the eukaryotic ribosome and its translational states in situ |
| title_sort | structures of the eukaryotic ribosome and its translational states in situ |
| url | https://doi.org/10.1038/s41467-022-34997-w |
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