Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors fo...
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JCDR Research and Publications Private Limited
2015-06-01
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Series: | Journal of Clinical and Diagnostic Research |
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Online Access: | https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf |
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author | Thomas V. Paul Sivan Arul Selvan Hesarghatta Shyamasunder Asha Nihal Thomas Krishnan Venkatesh Anil Thomas Oommen Thomas Mathai MandalamSubramanian Seshadri |
author_facet | Thomas V. Paul Sivan Arul Selvan Hesarghatta Shyamasunder Asha Nihal Thomas Krishnan Venkatesh Anil Thomas Oommen Thomas Mathai MandalamSubramanian Seshadri |
author_sort | Thomas V. Paul |
collection | DOAJ |
description | Background: Non-communicable diseases like hip fractures are
a significant problem in a developing country like India. The risk
factors for hip fractures vary according to local practices and the
availability of preventive health care delivery systems. There is
paucity of data on risk factors for hip fracture in the south Indian
population.
Aim: This study was undertaken to assess risk factors associated
with femoral neck (FN) fracture in South Indian postmenopausal
women along with subsequent one year mortality.
Materials and Methods: One hundred four postmenopausal
women with FN fracture and 104 age and BMI matched controls
were included. Sedative use, visual impairment and other relevant
risk factors were assessed. Bone biochemistry and Bone Mineral
Density (BMD) were evaluated. A telephonic interview was done at
the end of one year to ascertain the well-being.
Results: Sedative use, visual impairment, low FN BMD and
vitamin-D deficiency (<20 ng/ml) were seen more in fracture
subjects compared to controls (p≤0.05). At the end of one year,
20% of the fracture subjects and 5% of the controls had died
(p=0.001).
Conclusion: Risk factors identified in our study are potentially
correctable, and needs special attention in an Indian context to
prevent hip fractures. |
first_indexed | 2024-12-12T02:57:32Z |
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id | doaj.art-61571931d04844a5a608f2c5f9aa585f |
institution | Directory Open Access Journal |
issn | 2249-782X 0973-709X |
language | English |
last_indexed | 2024-12-12T02:57:32Z |
publishDate | 2015-06-01 |
publisher | JCDR Research and Publications Private Limited |
record_format | Article |
series | Journal of Clinical and Diagnostic Research |
spelling | doaj.art-61571931d04844a5a608f2c5f9aa585f2022-12-22T00:40:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196OC19OC2210.7860/JCDR/2015/9444.6131Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot StudyThomas V. Paul0Sivan Arul Selvan1Hesarghatta Shyamasunder Asha2Nihal Thomas3Krishnan Venkatesh4Anil Thomas Oommen5Thomas Mathai6MandalamSubramanian Seshadri7Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Tutor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Assistant Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Associate Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Assistant Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors for hip fracture in the south Indian population. Aim: This study was undertaken to assess risk factors associated with femoral neck (FN) fracture in South Indian postmenopausal women along with subsequent one year mortality. Materials and Methods: One hundred four postmenopausal women with FN fracture and 104 age and BMI matched controls were included. Sedative use, visual impairment and other relevant risk factors were assessed. Bone biochemistry and Bone Mineral Density (BMD) were evaluated. A telephonic interview was done at the end of one year to ascertain the well-being. Results: Sedative use, visual impairment, low FN BMD and vitamin-D deficiency (<20 ng/ml) were seen more in fracture subjects compared to controls (p≤0.05). At the end of one year, 20% of the fracture subjects and 5% of the controls had died (p=0.001). Conclusion: Risk factors identified in our study are potentially correctable, and needs special attention in an Indian context to prevent hip fractures.https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdfsedative usevitamin-d deficiencyvisual impairment |
spellingShingle | Thomas V. Paul Sivan Arul Selvan Hesarghatta Shyamasunder Asha Nihal Thomas Krishnan Venkatesh Anil Thomas Oommen Thomas Mathai MandalamSubramanian Seshadri Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study Journal of Clinical and Diagnostic Research sedative use vitamin-d deficiency visual impairment |
title | Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study |
title_full | Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study |
title_fullStr | Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study |
title_full_unstemmed | Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study |
title_short | Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study |
title_sort | hypovitaminosis d and other risk factors of femoral neck fracture in south indian postmenopausal women a pilot study |
topic | sedative use vitamin-d deficiency visual impairment |
url | https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf |
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