Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study

Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors fo...

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Main Authors: Thomas V. Paul, Sivan Arul Selvan, Hesarghatta Shyamasunder Asha, Nihal Thomas, Krishnan Venkatesh, Anil Thomas Oommen, Thomas Mathai, MandalamSubramanian Seshadri
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf
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author Thomas V. Paul
Sivan Arul Selvan
Hesarghatta Shyamasunder Asha
Nihal Thomas
Krishnan Venkatesh
Anil Thomas Oommen
Thomas Mathai
MandalamSubramanian Seshadri
author_facet Thomas V. Paul
Sivan Arul Selvan
Hesarghatta Shyamasunder Asha
Nihal Thomas
Krishnan Venkatesh
Anil Thomas Oommen
Thomas Mathai
MandalamSubramanian Seshadri
author_sort Thomas V. Paul
collection DOAJ
description Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors for hip fracture in the south Indian population. Aim: This study was undertaken to assess risk factors associated with femoral neck (FN) fracture in South Indian postmenopausal women along with subsequent one year mortality. Materials and Methods: One hundred four postmenopausal women with FN fracture and 104 age and BMI matched controls were included. Sedative use, visual impairment and other relevant risk factors were assessed. Bone biochemistry and Bone Mineral Density (BMD) were evaluated. A telephonic interview was done at the end of one year to ascertain the well-being. Results: Sedative use, visual impairment, low FN BMD and vitamin-D deficiency (<20 ng/ml) were seen more in fracture subjects compared to controls (p≤0.05). At the end of one year, 20% of the fracture subjects and 5% of the controls had died (p=0.001). Conclusion: Risk factors identified in our study are potentially correctable, and needs special attention in an Indian context to prevent hip fractures.
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spelling doaj.art-61571931d04844a5a608f2c5f9aa585f2022-12-22T00:40:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196OC19OC2210.7860/JCDR/2015/9444.6131Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot StudyThomas V. Paul0Sivan Arul Selvan1Hesarghatta Shyamasunder Asha2Nihal Thomas3Krishnan Venkatesh4Anil Thomas Oommen5Thomas Mathai6MandalamSubramanian Seshadri7Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Tutor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Assistant Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Associate Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Assistant Professor, Department of Orthopedics, Christian Medical College, Vellore, India.Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors for hip fracture in the south Indian population. Aim: This study was undertaken to assess risk factors associated with femoral neck (FN) fracture in South Indian postmenopausal women along with subsequent one year mortality. Materials and Methods: One hundred four postmenopausal women with FN fracture and 104 age and BMI matched controls were included. Sedative use, visual impairment and other relevant risk factors were assessed. Bone biochemistry and Bone Mineral Density (BMD) were evaluated. A telephonic interview was done at the end of one year to ascertain the well-being. Results: Sedative use, visual impairment, low FN BMD and vitamin-D deficiency (<20 ng/ml) were seen more in fracture subjects compared to controls (p≤0.05). At the end of one year, 20% of the fracture subjects and 5% of the controls had died (p=0.001). Conclusion: Risk factors identified in our study are potentially correctable, and needs special attention in an Indian context to prevent hip fractures.https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdfsedative usevitamin-d deficiencyvisual impairment
spellingShingle Thomas V. Paul
Sivan Arul Selvan
Hesarghatta Shyamasunder Asha
Nihal Thomas
Krishnan Venkatesh
Anil Thomas Oommen
Thomas Mathai
MandalamSubramanian Seshadri
Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
Journal of Clinical and Diagnostic Research
sedative use
vitamin-d deficiency
visual impairment
title Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
title_full Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
title_fullStr Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
title_full_unstemmed Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
title_short Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
title_sort hypovitaminosis d and other risk factors of femoral neck fracture in south indian postmenopausal women a pilot study
topic sedative use
vitamin-d deficiency
visual impairment
url https://jcdr.net/articles/PDF/6131/9444_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf
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