The impact of high nicotine concentrations on the viability and cardiac differentiation of mesenchymal stromal cells: a barrier to regenerative therapy for smokers

The impact of high nicotine concentrations on the viability and cardiac differentiation of mesenchymal stromal cells: a barrier to regenerative therapy for smokers

Background: Current treatment methods are not successful in restoring the lost cardiomyocytes after injury. Stem cell-based strategies have attracted much attention in this regard. Smoking, as a strong cardiovascular risk factor, not only affects the cardiac cells adversely but also deteriorates the...

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Bibliographic Details
Main Authors: Maryam Gheisari, Shadi Nosrati, Shahrokh Zare, Mahintaj Dara, Samaneh Zolghadri, Iman Razeghian-Jahromi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
nicotine
mesenchymal stromal cells
viability
cardiac differentiation
cardiovascular risk factors
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1323691/full

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