Roles and inhibitors of FAK in cancer: current advances and future directions

Roles and inhibitors of FAK in cancer: current advances and future directions

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that exhibits high expression in various tumors and is associated with a poor prognosis. FAK activation promotes tumor growth, invasion, metastasis, and angiogenesis via both kinase-dependent and kinase-independent pathways. Moreover, FAK...

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Bibliographic Details
Main Authors:	Hui-Hui Hu, Sai-Qi Wang, Hai-Li Shang, Hui-Fang Lv, Bei-Bei Chen, She-Gan Gao, Xiao-Bing Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Series:	Frontiers in Pharmacology
Subjects:	focal adhesion kinase signal pathway drug resistance immune microenvironment inhibitor IN10018
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1274209/full

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