Heterogeneous pattern of gene expression driven by TTN mutation is involved in the construction of a prognosis model of lung squamous cell carcinoma

Heterogeneous pattern of gene expression driven by TTN mutation is involved in the construction of a prognosis model of lung squamous cell carcinoma

ObjectiveTo investigate the impact that TTN mutation had on the gene heterogeneity expression and prognosis in patients with lung adenocarcinoma.MethodsIn this study, the Cancer Genome Atlas (TCGA) dataset was used to analyze the TTN mutations in lung adenocarcinoma. Lung adenocarcinoma data was col...

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Bibliographic Details
Main Authors: Zhao Liu, Xiaowen Zhao, Ruihong Wang, Xiangyue Tang, Yuxiang Zhao, Guanghui Zhong, Xin Peng, Chunlin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
bioinformatics
lung squamous carcinoma
TTN
gene mutation
prognostic survival
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.916568/full

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