Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil

ABSTRACT BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of São Paulo, Brazil. DESI...

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Main Authors: Danielle Bivanco-Lima, Itamar de Souza Santos, Yuan-Pang Wang, Maria Carmen Viana, Laura Helena Andrade, Paulo Andrade Lotufo, Isabela Judith Martins Benseñor
Format: Article
Language:English
Published: Associação Paulista de Medicina 2021-06-01
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000400364&tlng=en
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author Danielle Bivanco-Lima
Itamar de Souza Santos
Yuan-Pang Wang
Maria Carmen Viana
Laura Helena Andrade
Paulo Andrade Lotufo
Isabela Judith Martins Benseñor
author_facet Danielle Bivanco-Lima
Itamar de Souza Santos
Yuan-Pang Wang
Maria Carmen Viana
Laura Helena Andrade
Paulo Andrade Lotufo
Isabela Judith Martins Benseñor
author_sort Danielle Bivanco-Lima
collection DOAJ
description ABSTRACT BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study in São Paulo (SP), Brazil. METHODS: This study evaluated 423 individuals without any lifetime diagnosis of major depression and 203 individuals with a previous diagnosis of major depression (n = 626). The participants underwent a psychiatric evaluation using a structured clinical interview (SCID-1), an anthropometric evaluation and a clinical evaluation that included blood pressure measurement and assessment of fasting blood glucose, lipid profile and physical activity levels. RESULTS: Individuals with histories of major depression were more likely to be female (P < 0.0001). Individuals with lifetime diagnoses of major depression were more likely to be current smokers (odds ratio, OR 1.61; 95% confidence interval, CI 1.01-2.59) and to have diabetes (OR 1.79; 95% CI 1.01-3.21); and less likely to be obese (OR 0.58; 95% CI 0.35-0.94). CONCLUSION: Individuals with major depression had higher odds of presenting tobacco smoking and diabetes, and lower odds of being obese. Healthcare professionals need to be aware of this, so as to increase the rates of diagnosis and treatment in this population.
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spelling doaj.art-61620d0de6464d41b1cf3a0869282c1b2022-12-21T17:21:36ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602021-06-01139436437110.1590/1516-3180.2020.0054.r1.1802021Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, BrazilDanielle Bivanco-Limahttps://orcid.org/0000-0001-9243-0232Itamar de Souza Santoshttps://orcid.org/0000-0003-3212-8466Yuan-Pang Wanghttps://orcid.org/0000-0001-7076-8312Maria Carmen Vianahttps://orcid.org/0000-0002-0464-4845Laura Helena Andradehttps://orcid.org/0000-0002-2362-3521Paulo Andrade Lotufohttps://orcid.org/0000-0002-4856-8450Isabela Judith Martins Benseñorhttps://orcid.org/0000-0002-6723-5678ABSTRACT BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study in São Paulo (SP), Brazil. METHODS: This study evaluated 423 individuals without any lifetime diagnosis of major depression and 203 individuals with a previous diagnosis of major depression (n = 626). The participants underwent a psychiatric evaluation using a structured clinical interview (SCID-1), an anthropometric evaluation and a clinical evaluation that included blood pressure measurement and assessment of fasting blood glucose, lipid profile and physical activity levels. RESULTS: Individuals with histories of major depression were more likely to be female (P < 0.0001). Individuals with lifetime diagnoses of major depression were more likely to be current smokers (odds ratio, OR 1.61; 95% confidence interval, CI 1.01-2.59) and to have diabetes (OR 1.79; 95% CI 1.01-3.21); and less likely to be obese (OR 0.58; 95% CI 0.35-0.94). CONCLUSION: Individuals with major depression had higher odds of presenting tobacco smoking and diabetes, and lower odds of being obese. Healthcare professionals need to be aware of this, so as to increase the rates of diagnosis and treatment in this population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000400364&tlng=enDepressionRisk factorsCardiovascular diseasesDepressive disorder, majorDepressive disordersCardiovascular riskMajor depressive disorderDepressed individualsLifestyle and risk factors
spellingShingle Danielle Bivanco-Lima
Itamar de Souza Santos
Yuan-Pang Wang
Maria Carmen Viana
Laura Helena Andrade
Paulo Andrade Lotufo
Isabela Judith Martins Benseñor
Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
São Paulo Medical Journal
Depression
Risk factors
Cardiovascular diseases
Depressive disorder, major
Depressive disorders
Cardiovascular risk
Major depressive disorder
Depressed individuals
Lifestyle and risk factors
title Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
title_full Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
title_fullStr Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
title_full_unstemmed Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
title_short Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
title_sort cardiovascular risk factors and major depressive disorder a cross sectional study in sao paulo brazil
topic Depression
Risk factors
Cardiovascular diseases
Depressive disorder, major
Depressive disorders
Cardiovascular risk
Major depressive disorder
Depressed individuals
Lifestyle and risk factors
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000400364&tlng=en
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