Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study

Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study

Abstract Background Efficacy of inhaled therapy such as Nitric Oxide (iNO) during mechanical ventilation may depend on airway patency. We hypothesized that airway closure and lung collapse, countered by positive end-expiratory pressure (PEEP), influence iNO efficacy. This could support the role of a...

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Detalles Bibliográficos
Autores principales: Mariangela Pellegrini, Mayson L. A. Sousa, Sebastian Dubo, Luca S. Menga, Vanessa Hsing, Martin Post, Laurent J. Brochard
Formato: Artículo
Lenguaje:English
Publicado: SpringerOpen 2024-09-01
Colección:Annals of Intensive Care
Materias:
(3 to 10) nitric oxide
Acute respiratory distress syndrome
Mechanical ventilation
Airway closure
Acceso en línea:https://doi.org/10.1186/s13613-024-01378-z

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