Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study

Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study

Abstract Background Efficacy of inhaled therapy such as Nitric Oxide (iNO) during mechanical ventilation may depend on airway patency. We hypothesized that airway closure and lung collapse, countered by positive end-expiratory pressure (PEEP), influence iNO efficacy. This could support the role of a...

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Dettagli Bibliografici
Autori principali:	Mariangela Pellegrini, Mayson L. A. Sousa, Sebastian Dubo, Luca S. Menga, Vanessa Hsing, Martin Post, Laurent J. Brochard
Natura:	Articolo
Lingua:	English
Pubblicazione:	SpringerOpen 2024-09-01
Serie:	Annals of Intensive Care
Soggetti:	(3 to 10) nitric oxide Acute respiratory distress syndrome Mechanical ventilation Airway closure
Accesso online:	https://doi.org/10.1186/s13613-024-01378-z

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