Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study
Abstract Background Efficacy of inhaled therapy such as Nitric Oxide (iNO) during mechanical ventilation may depend on airway patency. We hypothesized that airway closure and lung collapse, countered by positive end-expiratory pressure (PEEP), influence iNO efficacy. This could support the role of a...
Principais autores: | Mariangela Pellegrini, Mayson L. A. Sousa, Sebastian Dubo, Luca S. Menga, Vanessa Hsing, Martin Post, Laurent J. Brochard |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
SpringerOpen
2024-09-01
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coleção: | Annals of Intensive Care |
Assuntos: | |
Acesso em linha: | https://doi.org/10.1186/s13613-024-01378-z |
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