A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH

Ensuring the stability of zein nanoparticles at different pH levels is crucial for their application as nanocarriers. In this study, octenyl succinic anhydride-modified starch (OSA-modified starch) was employed to enhance the stability of zein nanoparticles against different pH levels by forming com...

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Main Authors: Linlin Wang, Pengjie Wang, Yi Li, Siyuan Liu, Lida Wu, Weibo Zhang, Chong Chen
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/13/2/303
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author Linlin Wang
Pengjie Wang
Yi Li
Siyuan Liu
Lida Wu
Weibo Zhang
Chong Chen
author_facet Linlin Wang
Pengjie Wang
Yi Li
Siyuan Liu
Lida Wu
Weibo Zhang
Chong Chen
author_sort Linlin Wang
collection DOAJ
description Ensuring the stability of zein nanoparticles at different pH levels is crucial for their application as nanocarriers. In this study, octenyl succinic anhydride-modified starch (OSA-modified starch) was employed to enhance the stability of zein nanoparticles against different pH levels by forming complex nanoparticles with OSA-modified starch. The effect of preparation pH on the stability of the zein/OSA-modified starch nanoparticles was investigated. Sedimentation occurred in zein nanoparticles as the pH reached the isoelectric point. However, the stability of zein nanoparticles at various pH levels significantly improved after adding OSA-modified starch to form zein/OSA-modified starch nanoparticles regardless of whether they were prepared under acidic or alkaline pH conditions. Notably, the stability of zein/OSA-modified starch nanoparticles prepared at an acidic pH was higher than that of those prepared at an alkaline pH, thereby highlighting the critical role of the preparation pH for zein/OSA-modified starch in maintaining the stability of zein. The stable zein/OSA-modified starch nanoparticles developed in this study exhibit significant potential for use in delivery systems across various pH environments.
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spelling doaj.art-6162f0f62c49414684a351acc714278b2024-01-29T13:52:34ZengMDPI AGFoods2304-81582024-01-0113230310.3390/foods13020303A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pHLinlin Wang0Pengjie Wang1Yi Li2Siyuan Liu3Lida Wu4Weibo Zhang5Chong Chen6College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Government, Department of Nutrition and Health, China Agricultural University, Beijing 100193, ChinaJilin COFCO Biochemistry Co., Ltd., Changchun 130033, ChinaKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Government, Department of Nutrition and Health, China Agricultural University, Beijing 100193, ChinaJilin COFCO Biochemistry Co., Ltd., Changchun 130033, ChinaKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Government, Department of Nutrition and Health, China Agricultural University, Beijing 100193, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaEnsuring the stability of zein nanoparticles at different pH levels is crucial for their application as nanocarriers. In this study, octenyl succinic anhydride-modified starch (OSA-modified starch) was employed to enhance the stability of zein nanoparticles against different pH levels by forming complex nanoparticles with OSA-modified starch. The effect of preparation pH on the stability of the zein/OSA-modified starch nanoparticles was investigated. Sedimentation occurred in zein nanoparticles as the pH reached the isoelectric point. However, the stability of zein nanoparticles at various pH levels significantly improved after adding OSA-modified starch to form zein/OSA-modified starch nanoparticles regardless of whether they were prepared under acidic or alkaline pH conditions. Notably, the stability of zein/OSA-modified starch nanoparticles prepared at an acidic pH was higher than that of those prepared at an alkaline pH, thereby highlighting the critical role of the preparation pH for zein/OSA-modified starch in maintaining the stability of zein. The stable zein/OSA-modified starch nanoparticles developed in this study exhibit significant potential for use in delivery systems across various pH environments.https://www.mdpi.com/2304-8158/13/2/303zeinOSA-modified starchnanoparticlestability
spellingShingle Linlin Wang
Pengjie Wang
Yi Li
Siyuan Liu
Lida Wu
Weibo Zhang
Chong Chen
A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
Foods
zein
OSA-modified starch
nanoparticle
stability
title A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
title_full A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
title_fullStr A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
title_full_unstemmed A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
title_short A Novel Strategy to Enhance the pH Stability of Zein Particles through Octenyl Succinic Anhydride-Modified Starch: The Role of Preparation pH
title_sort novel strategy to enhance the ph stability of zein particles through octenyl succinic anhydride modified starch the role of preparation ph
topic zein
OSA-modified starch
nanoparticle
stability
url https://www.mdpi.com/2304-8158/13/2/303
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