Activation of JNK signaling mediates amyloid-ß-dependent cell death.

Activation of JNK signaling mediates amyloid-ß-dependent cell death.

Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular alterations th...

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Bibliographic Details
Main Authors: Meghana Tare, Rohan M Modi, Jaison J Nainaparampil, Oorvashi Roy Puli, Shimpi Bedi, Pedro Fernandez-Funez, Madhuri Kango-Singh, Amit Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3173392?pdf=render

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