Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature

The prevalence of pancreatic cysts has been rising due to the widespread use of cross-sectional imaging (CT scan and MRI) of the abdomen. While most pancreatic cysts are benign and do not require treatment or surveillance, a significant minority are premalignant and rarely malignant. The risk strati...

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Main Authors: Ritu R. Singh, Harishankar Gopakumar, Neil R. Sharma
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/3/550
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author Ritu R. Singh
Harishankar Gopakumar
Neil R. Sharma
author_facet Ritu R. Singh
Harishankar Gopakumar
Neil R. Sharma
author_sort Ritu R. Singh
collection DOAJ
description The prevalence of pancreatic cysts has been rising due to the widespread use of cross-sectional imaging (CT scan and MRI) of the abdomen. While most pancreatic cysts are benign and do not require treatment or surveillance, a significant minority are premalignant and rarely malignant. The risk stratification of these lesions is not straightforward, and individual risk assessment, cyst size, distribution, and alarming morphologic features (when present) can guide the next steps in management. Neoplastic pancreatic cysts are mucinous or non-mucinous. Endoscopic ultrasound with fine-needle aspiration is often required to classify pancreatic cysts into mucinous and non-mucinous cysts and to assess the malignant potential. Advances in endoscopic techniques (confocal laser endomicroscopy, microforceps biopsy) can provide a definitive diagnosis of pancreatic cysts in some cases; however, the use of these techniques involves a higher risk of adverse events.
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spelling doaj.art-61695e90c61c48be80336f5df216e4352023-11-16T16:26:25ZengMDPI AGDiagnostics2075-44182023-02-0113355010.3390/diagnostics13030550Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the LiteratureRitu R. Singh0Harishankar Gopakumar1Neil R. Sharma2Parkview Cancer Institute (PCI), Parkview Regional Medical Center, Fort Wayne, IN 46845, USADivision of Gastroenterology and Hepatology, University of Illinois College of Medicine, Peoria, IL 61656, USAParkview Cancer Institute (PCI), Parkview Regional Medical Center, Fort Wayne, IN 46845, USAThe prevalence of pancreatic cysts has been rising due to the widespread use of cross-sectional imaging (CT scan and MRI) of the abdomen. While most pancreatic cysts are benign and do not require treatment or surveillance, a significant minority are premalignant and rarely malignant. The risk stratification of these lesions is not straightforward, and individual risk assessment, cyst size, distribution, and alarming morphologic features (when present) can guide the next steps in management. Neoplastic pancreatic cysts are mucinous or non-mucinous. Endoscopic ultrasound with fine-needle aspiration is often required to classify pancreatic cysts into mucinous and non-mucinous cysts and to assess the malignant potential. Advances in endoscopic techniques (confocal laser endomicroscopy, microforceps biopsy) can provide a definitive diagnosis of pancreatic cysts in some cases; however, the use of these techniques involves a higher risk of adverse events.https://www.mdpi.com/2075-4418/13/3/550pancreatic cystic lesionsendoscopic ultrasoundfine needle aspirationsurveillanceintraductal papillary mucinous neoplasmmucinous cyst
spellingShingle Ritu R. Singh
Harishankar Gopakumar
Neil R. Sharma
Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
Diagnostics
pancreatic cystic lesions
endoscopic ultrasound
fine needle aspiration
surveillance
intraductal papillary mucinous neoplasm
mucinous cyst
title Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
title_full Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
title_fullStr Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
title_full_unstemmed Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
title_short Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature
title_sort diagnosis and management of pancreatic cysts a comprehensive review of the literature
topic pancreatic cystic lesions
endoscopic ultrasound
fine needle aspiration
surveillance
intraductal papillary mucinous neoplasm
mucinous cyst
url https://www.mdpi.com/2075-4418/13/3/550
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