Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer

We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced...

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Main Authors: M. Sánchez Pérez, P. Jiménez Marrero, D. Kim Lee, M.P. Neumann, N. Jorge Pérez, C. Hernández Hernández, S. Hernández Escobar, R. Marrero Domínguez
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442017300438
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author M. Sánchez Pérez
P. Jiménez Marrero
D. Kim Lee
M.P. Neumann
N. Jorge Pérez
C. Hernández Hernández
S. Hernández Escobar
R. Marrero Domínguez
author_facet M. Sánchez Pérez
P. Jiménez Marrero
D. Kim Lee
M.P. Neumann
N. Jorge Pérez
C. Hernández Hernández
S. Hernández Escobar
R. Marrero Domínguez
author_sort M. Sánchez Pérez
collection DOAJ
description We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle.
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spelling doaj.art-616ad983f49749b6b104764cdd18c36c2022-12-22T00:51:00ZengElsevierUrology Case Reports2214-44202017-07-0113C485010.1016/j.eucr.2017.03.027Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate CancerM. Sánchez PérezP. Jiménez MarreroD. Kim LeeM.P. NeumannN. Jorge PérezC. Hernández HernándezS. Hernández EscobarR. Marrero DomínguezWe hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle.http://www.sciencedirect.com/science/article/pii/S2214442017300438Prostate cancerLeydig cellAndrogen deprivation therapyLeydig tumorOrchiectomy
spellingShingle M. Sánchez Pérez
P. Jiménez Marrero
D. Kim Lee
M.P. Neumann
N. Jorge Pérez
C. Hernández Hernández
S. Hernández Escobar
R. Marrero Domínguez
Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
Urology Case Reports
Prostate cancer
Leydig cell
Androgen deprivation therapy
Leydig tumor
Orchiectomy
title Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_full Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_fullStr Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_full_unstemmed Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_short Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_sort incidental leydig cell tumor in patient with hormone resistant prostate cancer
topic Prostate cancer
Leydig cell
Androgen deprivation therapy
Leydig tumor
Orchiectomy
url http://www.sciencedirect.com/science/article/pii/S2214442017300438
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