Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals

Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals

Abstract Immunity to previously encountered viruses can alter response to unrelated pathogens. We reasoned that similar mechanism may also involve SARS-CoV-2 and thereby affect the specificity and the quality of the immune response against the virus. Here, we employed high-throughput next generation...

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Bibliographic Details
Main Authors: Mariliis Jaago, Annika Rähni, Nadežda Pupina, Arno Pihlak, Helle Sadam, Jürgen Tuvikene, Annela Avarlaid, Anu Planken, Margus Planken, Liina Haring, Eero Vasar, Miljana Baćević, France Lambert, Eija Kalso, Pirkko Pussinen, Pentti J. Tienari, Antti Vaheri, Dan Lindholm, Tõnis Timmusk, Amir M. Ghaemmaghami, Kaia Palm
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20849-6

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