Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures

The mechanism of self-assembly by short-chain peptides (oligopeptides) – the process by which their molecules spontaneously form an ordered structure – has received much attention recently. Selfassembling phenylalanine oligopeptides have been of particular interest due to their potential as an effec...

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Main Authors: A. S. Morozova, E. O. Kudryavtseva, S. A. Ziganshina, M. A. Ziganshin, A. A. Bukharaev
Format: Article
Language:English
Published: Kazan Federal University 2023-12-01
Series:Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki
Subjects:
Online Access:https://uzakuesc.elpub.ru/jour/article/view/24
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author A. S. Morozova
E. O. Kudryavtseva
S. A. Ziganshina
M. A. Ziganshin
A. A. Bukharaev
author_facet A. S. Morozova
E. O. Kudryavtseva
S. A. Ziganshina
M. A. Ziganshin
A. A. Bukharaev
author_sort A. S. Morozova
collection DOAJ
description The mechanism of self-assembly by short-chain peptides (oligopeptides) – the process by which their molecules spontaneously form an ordered structure – has received much attention recently. Selfassembling phenylalanine oligopeptides have been of particular interest due to their potential as an effective aid in the design of new functional materials. This paper considers the results of an SPM study on the ability of L-alanyl-L-phenylalanine to self-assemble into a thin film under the action of methanol vapor. The micro- and nanostructures that develop on the surface of amorphous films of this dipeptide were characterized. A method for monitoring the state of the surface of dipeptide films using atomic force spectroscopy was proposed. The results obtained contribute to the development of approaches for the controlled selfassembly of oligopeptides used to produce new biocompatible materials and environmentally friendly micro- and nanodevices that would help solve various problems in the medical, environmental, and energy fields.
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spelling doaj.art-616d3e9a230243e0bd33024ef8e3a1162024-03-17T16:27:33ZengKazan Federal UniversityUčënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki2542-064X2500-218X2023-12-01165110.26907/2542-064X.2023.1.37-4823Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and NanostructuresA. S. Morozova0E. O. Kudryavtseva1S. A. Ziganshina2M. A. Ziganshin3A. A. Bukharaev4Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center, Russian Academy of SciencesZavoisky Physical-Technical Institute, FRC Kazan Scientific Center, Russian Academy of Sciences; Kazan Federal UniversityZavoisky Physical-Technical Institute, FRC Kazan Scientific Center, Russian Academy of Sciences; Kazan Federal UniversityKazan Federal UniversityZavoisky Physical-Technical Institute, FRC Kazan Scientific Center, Russian Academy of SciencesThe mechanism of self-assembly by short-chain peptides (oligopeptides) – the process by which their molecules spontaneously form an ordered structure – has received much attention recently. Selfassembling phenylalanine oligopeptides have been of particular interest due to their potential as an effective aid in the design of new functional materials. This paper considers the results of an SPM study on the ability of L-alanyl-L-phenylalanine to self-assemble into a thin film under the action of methanol vapor. The micro- and nanostructures that develop on the surface of amorphous films of this dipeptide were characterized. A method for monitoring the state of the surface of dipeptide films using atomic force spectroscopy was proposed. The results obtained contribute to the development of approaches for the controlled selfassembly of oligopeptides used to produce new biocompatible materials and environmentally friendly micro- and nanodevices that would help solve various problems in the medical, environmental, and energy fields.https://uzakuesc.elpub.ru/jour/article/view/24dipeptidesself-assemblythin filmsmicrostructuresnanostructuresatomic force microscopy
spellingShingle A. S. Morozova
E. O. Kudryavtseva
S. A. Ziganshina
M. A. Ziganshin
A. A. Bukharaev
Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki
dipeptides
self-assembly
thin films
microstructures
nanostructures
atomic force microscopy
title Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
title_full Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
title_fullStr Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
title_full_unstemmed Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
title_short Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures
title_sort self assembly of the dipeptide l alanyl l phenylalanine under the action of methanol vapor with the formation of micro and nanostructures
topic dipeptides
self-assembly
thin films
microstructures
nanostructures
atomic force microscopy
url https://uzakuesc.elpub.ru/jour/article/view/24
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AT saziganshina selfassemblyofthedipeptidelalanyllphenylalanineundertheactionofmethanolvaporwiththeformationofmicroandnanostructures
AT maziganshin selfassemblyofthedipeptidelalanyllphenylalanineundertheactionofmethanolvaporwiththeformationofmicroandnanostructures
AT aabukharaev selfassemblyofthedipeptidelalanyllphenylalanineundertheactionofmethanolvaporwiththeformationofmicroandnanostructures