Integrative Analyses Identify Potential Key Genes and Calcium-Signaling Pathway in Familial Atrioventricular Nodal Reentrant Tachycardia Using Whole-Exome Sequencing

Integrative Analyses Identify Potential Key Genes and Calcium-Signaling Pathway in Familial Atrioventricular Nodal Reentrant Tachycardia Using Whole-Exome Sequencing

BackgroundAtrioventricular nodal reentrant tachycardia (AVNRT) is a common arrhythmia. Growing evidence suggests that family aggregation and genetic factors are involved in AVNRT. However, in families with a history of AVNRT, disease-causing genes have not been reported.ObjectiveTo investigate the g...

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Bibliographic Details
Main Authors: Jichang Huang, Rong Luo, Chenqing Zheng, Xin Cao, Yuncai Zhu, Tao He, Mingjiang Liu, Zhenglin Yang, Xiushan Wu, Xiaoping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
familial AVNRT
arrhythmia
whole-exome sequencing
pathogenic genes
calcium-signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.910826/full

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