Genetic diversity of merozoite surface protein-1 C-terminal 42 kDa of Plasmodium falciparum (PfMSP-142) may be greater than previously known in global isolates

Genetic diversity of merozoite surface protein-1 C-terminal 42 kDa of Plasmodium falciparum (PfMSP-142) may be greater than previously known in global isolates

Abstract Background The C-terminal 42 kDa region of merozoite surface protein-1 of Plasmodium falciparum (PfMSP-142) is the target of an immune response. It has been recognised as one of the promising candidate antigens for a blood-stage malaria vaccine. Genetic structure of PfMSP-142 has been consi...

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Bibliographic Details
Main Authors: Thị Lam Thái, Hojong Jun, Jinyoung Lee, Jung-Mi Kang, Hương Giang Lê, Khin Lin, Kyaw Zin Thant, Woon-Mok Sohn, Tong-Soo Kim, Byoung-Kuk Na
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Parasites & Vectors
Subjects:
Plasmodium falciparum
PfMSP-142
Myanmar
Polymorphism
Natural selection
Online Access:http://link.springer.com/article/10.1186/s13071-018-3027-x

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