A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects
A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.
Podrobná bibliografie
| Hlavní autoři: |
A. Petersen,
A. Princ,
G. Korus,
A. Ellinghaus,
H. Leemhuis,
A. Herrera,
A. Klaumünzer,
S. Schreivogel,
A. Woloszyk,
K. Schmidt-Bleek,
S. Geissler,
I. Heschel,
G. N. Duda |
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| Médium: | Článek
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| Jazyk: | English |
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| Vydáno: |
Nature Portfolio
2018-10-01
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| Edice: | Nature Communications
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| On-line přístup: | https://doi.org/10.1038/s41467-018-06504-7
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