A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects

A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects

A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.

Podrobná bibliografie
Hlavní autoři: A. Petersen, A. Princ, G. Korus, A. Ellinghaus, H. Leemhuis, A. Herrera, A. Klaumünzer, S. Schreivogel, A. Woloszyk, K. Schmidt-Bleek, S. Geissler, I. Heschel, G. N. Duda
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2018-10-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-018-06504-7

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