A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects
A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.
Autores principales: | , , , , , , , , , , , , |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Nature Portfolio
2018-10-01
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Colección: | Nature Communications |
Acceso en línea: | https://doi.org/10.1038/s41467-018-06504-7 |