A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects
A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.
Main Authors: | , , , , , , , , , , , , |
---|---|
פורמט: | Article |
שפה: | English |
יצא לאור: |
Nature Portfolio
2018-10-01
|
סדרה: | Nature Communications |
גישה מקוונת: | https://doi.org/10.1038/s41467-018-06504-7 |