miR-451 Loaded Exosomes Are Released by the Renal Cells in Response to Injury and Associated With Reduced Kidney Function in Human

miR-451 Loaded Exosomes Are Released by the Renal Cells in Response to Injury and Associated With Reduced Kidney Function in Human

Micro-RNAs (miRs) encapsulated inside urinary exosomes (uEs) have the potential as early biomarkers. Previously, we reported that a rise in uE miR-451 predicted albuminuria in diabetic rats; however, whether the rise was protective or detrimental, and occurred in response to injury or general hyperg...

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Bibliographic Details
Main Authors: Manju Kumari, Aradhana Mohan, Carolyn M. Ecelbarger, Anita Saxena, Amit Gupta, Narayan Prasad, Swasti Tiwari
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Physiology
Subjects:
urinary exosomes
chronic kidney disease
diabetic kidney disease
micro-RNA
albuminuria
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00234/full

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