Ion-Sensitive Field-Effect Transistor for Biological Sensing

In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advanc...

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Main Authors: Chang-Soo Lee, Sang Kyu Kim, Moonil Kim
Format: Article
Language:English
Published: MDPI AG 2009-09-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/9/7111/
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author Chang-Soo Lee
Sang Kyu Kim
Moonil Kim
author_facet Chang-Soo Lee
Sang Kyu Kim
Moonil Kim
author_sort Chang-Soo Lee
collection DOAJ
description In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells.
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spelling doaj.art-6175926f5756410892d93fc04ae54b652022-12-22T04:22:08ZengMDPI AGSensors1424-82202009-09-01997111713110.3390/s90907111Ion-Sensitive Field-Effect Transistor for Biological SensingChang-Soo LeeSang Kyu KimMoonil KimIn recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells.http://www.mdpi.com/1424-8220/9/9/7111/ISFETion-sensitive field-effect transistorbiosensorbiomolecules
spellingShingle Chang-Soo Lee
Sang Kyu Kim
Moonil Kim
Ion-Sensitive Field-Effect Transistor for Biological Sensing
Sensors
ISFET
ion-sensitive field-effect transistor
biosensor
biomolecules
title Ion-Sensitive Field-Effect Transistor for Biological Sensing
title_full Ion-Sensitive Field-Effect Transistor for Biological Sensing
title_fullStr Ion-Sensitive Field-Effect Transistor for Biological Sensing
title_full_unstemmed Ion-Sensitive Field-Effect Transistor for Biological Sensing
title_short Ion-Sensitive Field-Effect Transistor for Biological Sensing
title_sort ion sensitive field effect transistor for biological sensing
topic ISFET
ion-sensitive field-effect transistor
biosensor
biomolecules
url http://www.mdpi.com/1424-8220/9/9/7111/
work_keys_str_mv AT changsoolee ionsensitivefieldeffecttransistorforbiologicalsensing
AT sangkyukim ionsensitivefieldeffecttransistorforbiologicalsensing
AT moonilkim ionsensitivefieldeffecttransistorforbiologicalsensing