Ion-Sensitive Field-Effect Transistor for Biological Sensing
In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advanc...
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Format: | Article |
Language: | English |
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MDPI AG
2009-09-01
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Series: | Sensors |
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Online Access: | http://www.mdpi.com/1424-8220/9/9/7111/ |
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author | Chang-Soo Lee Sang Kyu Kim Moonil Kim |
author_facet | Chang-Soo Lee Sang Kyu Kim Moonil Kim |
author_sort | Chang-Soo Lee |
collection | DOAJ |
description | In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells. |
first_indexed | 2024-04-11T13:23:29Z |
format | Article |
id | doaj.art-6175926f5756410892d93fc04ae54b65 |
institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-04-11T13:23:29Z |
publishDate | 2009-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Sensors |
spelling | doaj.art-6175926f5756410892d93fc04ae54b652022-12-22T04:22:08ZengMDPI AGSensors1424-82202009-09-01997111713110.3390/s90907111Ion-Sensitive Field-Effect Transistor for Biological SensingChang-Soo LeeSang Kyu KimMoonil KimIn recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells.http://www.mdpi.com/1424-8220/9/9/7111/ISFETion-sensitive field-effect transistorbiosensorbiomolecules |
spellingShingle | Chang-Soo Lee Sang Kyu Kim Moonil Kim Ion-Sensitive Field-Effect Transistor for Biological Sensing Sensors ISFET ion-sensitive field-effect transistor biosensor biomolecules |
title | Ion-Sensitive Field-Effect Transistor for Biological Sensing |
title_full | Ion-Sensitive Field-Effect Transistor for Biological Sensing |
title_fullStr | Ion-Sensitive Field-Effect Transistor for Biological Sensing |
title_full_unstemmed | Ion-Sensitive Field-Effect Transistor for Biological Sensing |
title_short | Ion-Sensitive Field-Effect Transistor for Biological Sensing |
title_sort | ion sensitive field effect transistor for biological sensing |
topic | ISFET ion-sensitive field-effect transistor biosensor biomolecules |
url | http://www.mdpi.com/1424-8220/9/9/7111/ |
work_keys_str_mv | AT changsoolee ionsensitivefieldeffecttransistorforbiologicalsensing AT sangkyukim ionsensitivefieldeffecttransistorforbiologicalsensing AT moonilkim ionsensitivefieldeffecttransistorforbiologicalsensing |