RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits

RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of DNA polymerase and errors are amplified >1000-fold due to translation. However, current methods to measure RNA polymera...

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Bibliographic Details
Main Author:	Lucas B Carey
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2015-12-01
Series:	eLife
Subjects:	RNA-seq RNA polymerase biological errors splicing
Online Access:	https://elifesciences.org/articles/09945

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