Viable mpox virus in the environment of a patient room
We conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Envir...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971223000929 |
| _version_ | 1797850504470986752 |
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| author | Kalisvar Marimuthu Judith Chui Ching Wong Poh Lian Lim Sophie Octavia Xiaowei Huan Yi Kai Ng Jun Jing Yang Stephanie Sutjipto Kyaw Zaw Linn Yin Xiang Setoh Chong Hui Clara Ong Jane Griffiths Sharifah Farhanah Thai Shawn Cheok Nur Ashikin Binti Sulaiman Sipaco Barbara Congcong Erica Sena Neves Liang Hui Loo Luqman Hakim Shuzhen Sim Merrill Lim Mohammad Nazeem Shawn Vasoo Kwok Wai Tham Oon Tek Ng Lee Ching Ng |
| author_facet | Kalisvar Marimuthu Judith Chui Ching Wong Poh Lian Lim Sophie Octavia Xiaowei Huan Yi Kai Ng Jun Jing Yang Stephanie Sutjipto Kyaw Zaw Linn Yin Xiang Setoh Chong Hui Clara Ong Jane Griffiths Sharifah Farhanah Thai Shawn Cheok Nur Ashikin Binti Sulaiman Sipaco Barbara Congcong Erica Sena Neves Liang Hui Loo Luqman Hakim Shuzhen Sim Merrill Lim Mohammad Nazeem Shawn Vasoo Kwok Wai Tham Oon Tek Ng Lee Ching Ng |
| author_sort | Kalisvar Marimuthu |
| collection | DOAJ |
| description | We conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Environmental sampling was conducted in a negative pressure room with 12 unidirectional high efficiency particulate air filter (HEPA) air changes per hour and daily cleaning of the surfaces. A total of 179 environmental samples were collected on days 7, 8, 13, and 21 of illness. Among the days of sampling, air, surface, and dust contamination showed the highest contamination rates on day 7 and 8 of illness, with a gradual decline to the lowest contamination level by day 21. Viable MPXV was isolated from surfaces and dust samples and no viable virus was isolated from the air and water samples. |
| first_indexed | 2024-04-09T19:01:11Z |
| format | Article |
| id | doaj.art-61876aaf8c1243479e8cdb9c33c7f06a |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-04-09T19:01:11Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-61876aaf8c1243479e8cdb9c33c7f06a2023-04-08T05:10:46ZengElsevierInternational Journal of Infectious Diseases1201-97122023-06-011314045Viable mpox virus in the environment of a patient roomKalisvar Marimuthu0Judith Chui Ching Wong1Poh Lian Lim2Sophie Octavia3Xiaowei Huan4Yi Kai Ng5Jun Jing Yang6Stephanie Sutjipto7Kyaw Zaw Linn8Yin Xiang Setoh9Chong Hui Clara Ong10Jane Griffiths11Sharifah Farhanah12Thai Shawn Cheok13Nur Ashikin Binti Sulaiman14Sipaco Barbara Congcong15Erica Sena Neves16Liang Hui Loo17Luqman Hakim18Shuzhen Sim19Merrill Lim20Mohammad Nazeem21Shawn Vasoo22Kwok Wai Tham23Oon Tek Ng24Lee Ching Ng25National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Corresponding author. Tel: +65 63577924; fax: +65 62524056Environmental Health Institute, National Environment Agency, SingaporeNational Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, SingaporeEnvironmental Health Institute, National Environment Agency, Singapore; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, AustraliaDepartment of Infectious Diseases, Tan Tock Seng Hospital, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeNational Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, SingaporeNational Centre for Infectious Diseases, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore; Environmental Health Institute, National Environment Agency, Singapore; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane City, AustraliaDepartment of Infectious Diseases, Tan Tock Seng Hospital, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeDepartment of Infectious Diseases, Tan Tock Seng Hospital, SingaporeDepartment of Infectious Diseases, Tan Tock Seng Hospital, SingaporeNational Centre for Infectious Diseases, SingaporeNational Centre for Infectious Diseases, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeDepartment of Infectious Diseases, Tan Tock Seng Hospital, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeEnvironmental Health Institute, National Environment Agency, SingaporeNational Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, SingaporeDepartment of the Built Environment, National University of Singapore, SingaporeNational Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, SingaporeEnvironmental Health Institute, National Environment Agency, Singapore; School of Biological Sciences, Nanyang Technological University, SingaporeWe conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Environmental sampling was conducted in a negative pressure room with 12 unidirectional high efficiency particulate air filter (HEPA) air changes per hour and daily cleaning of the surfaces. A total of 179 environmental samples were collected on days 7, 8, 13, and 21 of illness. Among the days of sampling, air, surface, and dust contamination showed the highest contamination rates on day 7 and 8 of illness, with a gradual decline to the lowest contamination level by day 21. Viable MPXV was isolated from surfaces and dust samples and no viable virus was isolated from the air and water samples.http://www.sciencedirect.com/science/article/pii/S1201971223000929Mpox virus (MPXV)Environmental contaminationModes of transmissionSurface contaminationAirborne transmissionFormite |
| spellingShingle | Kalisvar Marimuthu Judith Chui Ching Wong Poh Lian Lim Sophie Octavia Xiaowei Huan Yi Kai Ng Jun Jing Yang Stephanie Sutjipto Kyaw Zaw Linn Yin Xiang Setoh Chong Hui Clara Ong Jane Griffiths Sharifah Farhanah Thai Shawn Cheok Nur Ashikin Binti Sulaiman Sipaco Barbara Congcong Erica Sena Neves Liang Hui Loo Luqman Hakim Shuzhen Sim Merrill Lim Mohammad Nazeem Shawn Vasoo Kwok Wai Tham Oon Tek Ng Lee Ching Ng Viable mpox virus in the environment of a patient room International Journal of Infectious Diseases Mpox virus (MPXV) Environmental contamination Modes of transmission Surface contamination Airborne transmission Formite |
| title | Viable mpox virus in the environment of a patient room |
| title_full | Viable mpox virus in the environment of a patient room |
| title_fullStr | Viable mpox virus in the environment of a patient room |
| title_full_unstemmed | Viable mpox virus in the environment of a patient room |
| title_short | Viable mpox virus in the environment of a patient room |
| title_sort | viable mpox virus in the environment of a patient room |
| topic | Mpox virus (MPXV) Environmental contamination Modes of transmission Surface contamination Airborne transmission Formite |
| url | http://www.sciencedirect.com/science/article/pii/S1201971223000929 |
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