Biofilm-Related Infection: Diagnosis, Treatment, and Prevention

Biofilms can cause infections associated with orthopedic devices, endotracheal tubes, intravenous catheters, urinary catheters, and tissue fillers as well as chronic wound infections, and chronic lung infections in cystic fibrosis patients. The diagnosis and treatment of biofilm-related infections a...

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Main Authors: Ayşe KALKANCI, Özlem GÜZEL TUNÇCAN
Format: Article
Language:Turkish
Published: Galenos Yayinevi 2019-12-01
Series:Mediterranean Journal of Infection, Microbes and Antimicrobials
Subjects:
Online Access:http://mjima.org/text.php?&id=173
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author Ayşe KALKANCI
Özlem GÜZEL TUNÇCAN
author_facet Ayşe KALKANCI
Özlem GÜZEL TUNÇCAN
author_sort Ayşe KALKANCI
collection DOAJ
description Biofilms can cause infections associated with orthopedic devices, endotracheal tubes, intravenous catheters, urinary catheters, and tissue fillers as well as chronic wound infections, and chronic lung infections in cystic fibrosis patients. The diagnosis and treatment of biofilm-related infections are difficult. For diagnosis, there are methods for imaging the biofilm at the site of infection, as well as microbiological methods for identifying the microorganism causing the biofilm infection. In recent years, different therapeutic approaches have been investigated to address difficulties in the diagnosis and treatment of biofilm-related infections, particularly problems such as antibiotic resistance. Together with various antibiotics, it is predicted that antimicrobial photodynamic therapy, antimicrobial lock therapy, and various bioactive molecules/enzymes with antibiofilm activity will become more widely used as therapeutic models in the future. The aim of this paper was to review methods of diagnosis, treatment, and prevention of biofilm-related infections.
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spelling doaj.art-618808d9d39c4264ac464bafc35570f12023-02-15T16:08:26ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2019-12-01810.4274/mjima.galenos.2019.2019.18Biofilm-Related Infection: Diagnosis, Treatment, and PreventionAyşe KALKANCI0https://orcid.org/0000-0003-0961-7325Özlem GÜZEL TUNÇCAN1https://orcid.org/0000-0003-1611-0725Gazi University Faculty of Medicine, Department of Medical Microbiology, Ankara, TurkeyGazi University Faculty of Medicine, Clinic of Infectious Diseases and Clinical Microbiology, Ankara, TurkeyBiofilms can cause infections associated with orthopedic devices, endotracheal tubes, intravenous catheters, urinary catheters, and tissue fillers as well as chronic wound infections, and chronic lung infections in cystic fibrosis patients. The diagnosis and treatment of biofilm-related infections are difficult. For diagnosis, there are methods for imaging the biofilm at the site of infection, as well as microbiological methods for identifying the microorganism causing the biofilm infection. In recent years, different therapeutic approaches have been investigated to address difficulties in the diagnosis and treatment of biofilm-related infections, particularly problems such as antibiotic resistance. Together with various antibiotics, it is predicted that antimicrobial photodynamic therapy, antimicrobial lock therapy, and various bioactive molecules/enzymes with antibiofilm activity will become more widely used as therapeutic models in the future. The aim of this paper was to review methods of diagnosis, treatment, and prevention of biofilm-related infections.http://mjima.org/text.php?&id=173echinocandinschronic woundprosthetic joint infections“quorum-sensing” inhibitorsantibiotic-coated implants
spellingShingle Ayşe KALKANCI
Özlem GÜZEL TUNÇCAN
Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
Mediterranean Journal of Infection, Microbes and Antimicrobials
echinocandins
chronic wound
prosthetic joint infections
“quorum-sensing” inhibitors
antibiotic-coated implants
title Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
title_full Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
title_fullStr Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
title_full_unstemmed Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
title_short Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
title_sort biofilm related infection diagnosis treatment and prevention
topic echinocandins
chronic wound
prosthetic joint infections
“quorum-sensing” inhibitors
antibiotic-coated implants
url http://mjima.org/text.php?&id=173
work_keys_str_mv AT aysekalkanci biofilmrelatedinfectiondiagnosistreatmentandprevention
AT ozlemguzeltunccan biofilmrelatedinfectiondiagnosistreatmentandprevention