Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

Summary: New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here, we describe human monoclonal antibodies (mAb...

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Bibliographic Details
Main Authors: Taylor B. Engdahl, Natalia A. Kuzmina, Adam J. Ronk, Chad E. Mire, Matthew A. Hyde, Nurgun Kose, Matthew D. Josleyn, Rachel E. Sutton, Apoorva Mehta, Rachael M. Wolters, Nicole M. Lloyd, Francisca R. Valdivieso, Thomas G. Ksiazek, Jay W. Hooper, Alexander Bukreyev, James E. Crowe, Jr.
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
hantavirus
Bunyavirus
cross-reactivity
Sin Nombre virus
Andes virus
infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004198

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