It's easier to get along with the quiet neighbours

Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, ) suggests this is the exception not the rule. Rather it mi...

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Bibliographic Details
Main Author: Laurence D Hurst
Format: Article
Language:English
Published: Springer Nature 2017-09-01
Series:Molecular Systems Biology
Online Access:https://doi.org/10.15252/msb.20177961
Description
Summary:Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, ) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise.
ISSN:1744-4292