It's easier to get along with the quiet neighbours
Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, ) suggests this is the exception not the rule. Rather it mi...
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Format: | Article |
Language: | English |
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Springer Nature
2017-09-01
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Series: | Molecular Systems Biology |
Online Access: | https://doi.org/10.15252/msb.20177961 |
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author | Laurence D Hurst |
author_facet | Laurence D Hurst |
author_sort | Laurence D Hurst |
collection | DOAJ |
description | Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, ) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise. |
first_indexed | 2024-03-13T03:10:48Z |
format | Article |
id | doaj.art-618f46fdb8ab4d10accf9ae7fd0c6409 |
institution | Directory Open Access Journal |
issn | 1744-4292 |
language | English |
last_indexed | 2024-04-24T14:08:41Z |
publishDate | 2017-09-01 |
publisher | Springer Nature |
record_format | Article |
series | Molecular Systems Biology |
spelling | doaj.art-618f46fdb8ab4d10accf9ae7fd0c64092024-04-03T09:38:26ZengSpringer NatureMolecular Systems Biology1744-42922017-09-01139n/an/a10.15252/msb.20177961It's easier to get along with the quiet neighboursLaurence D Hurst0The Milner Centre for Evolution Biology and Biochemistry University of Bath Bath UKWhy are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, ) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise.https://doi.org/10.15252/msb.20177961 |
spellingShingle | Laurence D Hurst It's easier to get along with the quiet neighbours Molecular Systems Biology |
title | It's easier to get along with the quiet neighbours |
title_full | It's easier to get along with the quiet neighbours |
title_fullStr | It's easier to get along with the quiet neighbours |
title_full_unstemmed | It's easier to get along with the quiet neighbours |
title_short | It's easier to get along with the quiet neighbours |
title_sort | it s easier to get along with the quiet neighbours |
url | https://doi.org/10.15252/msb.20177961 |
work_keys_str_mv | AT laurencedhurst itseasiertogetalongwiththequietneighbours |