Buformin suppresses osteosarcoma via targeting AMPK signaling pathway
Buformin has been reported to be a powerful anticancer drug by activating the AMPK signal. Herein, we aimed to investigate the effects of buformin on osteosarcoma.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2020-06-01
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| Series: | Open Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/biol-2020-0041 |
| _version_ | 1818583521126514688 |
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| author | Ding Yan Lv Shiqiao Li Guangrun Cui Jinpeng Chen Yunzhen |
| author_facet | Ding Yan Lv Shiqiao Li Guangrun Cui Jinpeng Chen Yunzhen |
| author_sort | Ding Yan |
| collection | DOAJ |
| description | Buformin has been reported to be a powerful anticancer drug by activating the AMPK signal. Herein, we aimed to investigate the effects of buformin on osteosarcoma. |
| first_indexed | 2024-12-16T08:06:36Z |
| format | Article |
| id | doaj.art-619398036ef34e68a1f4d8305b1801a4 |
| institution | Directory Open Access Journal |
| issn | 2391-5412 |
| language | English |
| last_indexed | 2024-12-16T08:06:36Z |
| publishDate | 2020-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj.art-619398036ef34e68a1f4d8305b1801a42022-12-21T22:38:27ZengDe GruyterOpen Life Sciences2391-54122020-06-0115140941710.1515/biol-2020-0041biol-2020-0041Buformin suppresses osteosarcoma via targeting AMPK signaling pathwayDing Yan0Lv Shiqiao1Li Guangrun2Cui Jinpeng3Chen Yunzhen4Department of Spine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, No. 107 West Wenhua Road, Jinan 250012, Shandong Province, ChinaDepartment of Orthopedics, Yantaishan Hospital, Yantai 264000, ChinaDepartment of Spine, Yantai Yuhuangding Hospital Affiliated to Medical College of Qingdao University, Yantai 264000, ChinaClinical Laboratory, Yantaishan Hospital, Yantai 264000, ChinaDepartment of Spine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, No. 107 West Wenhua Road, Jinan 250012, Shandong Province, ChinaBuformin has been reported to be a powerful anticancer drug by activating the AMPK signal. Herein, we aimed to investigate the effects of buformin on osteosarcoma.https://doi.org/10.1515/biol-2020-0041buforminosteosarcomaampk signal pathwaysynergistic effect |
| spellingShingle | Ding Yan Lv Shiqiao Li Guangrun Cui Jinpeng Chen Yunzhen Buformin suppresses osteosarcoma via targeting AMPK signaling pathway Open Life Sciences buformin osteosarcoma ampk signal pathway synergistic effect |
| title | Buformin suppresses osteosarcoma via targeting AMPK signaling pathway |
| title_full | Buformin suppresses osteosarcoma via targeting AMPK signaling pathway |
| title_fullStr | Buformin suppresses osteosarcoma via targeting AMPK signaling pathway |
| title_full_unstemmed | Buformin suppresses osteosarcoma via targeting AMPK signaling pathway |
| title_short | Buformin suppresses osteosarcoma via targeting AMPK signaling pathway |
| title_sort | buformin suppresses osteosarcoma via targeting ampk signaling pathway |
| topic | buformin osteosarcoma ampk signal pathway synergistic effect |
| url | https://doi.org/10.1515/biol-2020-0041 |
| work_keys_str_mv | AT dingyan buforminsuppressesosteosarcomaviatargetingampksignalingpathway AT lvshiqiao buforminsuppressesosteosarcomaviatargetingampksignalingpathway AT liguangrun buforminsuppressesosteosarcomaviatargetingampksignalingpathway AT cuijinpeng buforminsuppressesosteosarcomaviatargetingampksignalingpathway AT chenyunzhen buforminsuppressesosteosarcomaviatargetingampksignalingpathway |