The Prevalence of PCOS in East Asia
Polycystic ovary syndrome (PCOS) has emerged as a significant international public health concern in East Asia and around the world. It is characterized by clinical manifestations such as oligo/anovulation, hyperandrogenism, and polycystic ovarian morphology, etc. The pathogenesis of PCOS is complex...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2023-12-01
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| Series: | Fertility & Reproduction |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S2661318223740031 |
| _version_ | 1797236996842717184 |
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| author | Rong Li |
| author_facet | Rong Li |
| author_sort | Rong Li |
| collection | DOAJ |
| description | Polycystic ovary syndrome (PCOS) has emerged as a significant international public health concern in East Asia and around the world. It is characterized by clinical manifestations such as oligo/anovulation, hyperandrogenism, and polycystic ovarian morphology, etc. The pathogenesis of PCOS is complex, involving the interaction of genetic and environmental factors. The prevalence of PCOS in China has reached 7.8% with variation across different regions, occupations, and age groups. Notably, the prevalence of PCOS among Chinese women has been increasing from 2010 to 2020. Similar upward trends in prevalence rates of PCOS have also been observed in other countries. The rise in prevalence is primarily driven by type III PCOS (O+P), while type IV PCOS (H+O+P) has remained relatively stable. PCOS is associated with significant metabolic consequences, including increased risk of impaired glucose tolerance and type 2 diabetes mellitus, atherogenic dyslipidemia, systemic inflammation due to increased secretion of pro-inflammatory factors by adipose tissue, non-alcoholic fatty liver disease, hypertension, and potential coagulation disorders. PCOS affects quality of life and can worsen anxiety and depression either due to its symptoms or due to the diagnosis of a chronic disease. Genetic studies have identified susceptibility loci for PCOS, shedding light on its genetic underpinnings. Treatment aims in PCOS include optimising healthy weight, improving underlying hormonal disturbances, prevention of future reproductive and metabolic complications, and improving quality of life. Effective intervention strategies for PCOS include pharmacological treatments, lifestyle modifications, and surgical treatments. |
| first_indexed | 2024-04-24T17:12:44Z |
| format | Article |
| id | doaj.art-6198891c85f244fda5e0944634f8bbdb |
| institution | Directory Open Access Journal |
| issn | 2661-3182 2661-3174 |
| language | English |
| last_indexed | 2024-04-24T17:12:44Z |
| publishDate | 2023-12-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Fertility & Reproduction |
| spelling | doaj.art-6198891c85f244fda5e0944634f8bbdb2024-03-28T07:54:19ZengWorld Scientific PublishingFertility & Reproduction2661-31822661-31742023-12-01050418918910.1142/S2661318223740031The Prevalence of PCOS in East AsiaRong Li0Professor, Peking University Third Hospital, ChinaPolycystic ovary syndrome (PCOS) has emerged as a significant international public health concern in East Asia and around the world. It is characterized by clinical manifestations such as oligo/anovulation, hyperandrogenism, and polycystic ovarian morphology, etc. The pathogenesis of PCOS is complex, involving the interaction of genetic and environmental factors. The prevalence of PCOS in China has reached 7.8% with variation across different regions, occupations, and age groups. Notably, the prevalence of PCOS among Chinese women has been increasing from 2010 to 2020. Similar upward trends in prevalence rates of PCOS have also been observed in other countries. The rise in prevalence is primarily driven by type III PCOS (O+P), while type IV PCOS (H+O+P) has remained relatively stable. PCOS is associated with significant metabolic consequences, including increased risk of impaired glucose tolerance and type 2 diabetes mellitus, atherogenic dyslipidemia, systemic inflammation due to increased secretion of pro-inflammatory factors by adipose tissue, non-alcoholic fatty liver disease, hypertension, and potential coagulation disorders. PCOS affects quality of life and can worsen anxiety and depression either due to its symptoms or due to the diagnosis of a chronic disease. Genetic studies have identified susceptibility loci for PCOS, shedding light on its genetic underpinnings. Treatment aims in PCOS include optimising healthy weight, improving underlying hormonal disturbances, prevention of future reproductive and metabolic complications, and improving quality of life. Effective intervention strategies for PCOS include pharmacological treatments, lifestyle modifications, and surgical treatments.https://www.worldscientific.com/doi/10.1142/S2661318223740031 |
| spellingShingle | Rong Li The Prevalence of PCOS in East Asia Fertility & Reproduction |
| title | The Prevalence of PCOS in East Asia |
| title_full | The Prevalence of PCOS in East Asia |
| title_fullStr | The Prevalence of PCOS in East Asia |
| title_full_unstemmed | The Prevalence of PCOS in East Asia |
| title_short | The Prevalence of PCOS in East Asia |
| title_sort | prevalence of pcos in east asia |
| url | https://www.worldscientific.com/doi/10.1142/S2661318223740031 |
| work_keys_str_mv | AT rongli theprevalenceofpcosineastasia AT rongli prevalenceofpcosineastasia |