A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects
This pilot study explored the feasibility of a moderate time-restricted feeding (TRF) intervention and its effects on adiposity and metabolism. For 10 weeks, a free-living TRF group delayed breakfast and advanced dinner by 1·5 h each. Changes in dietary intake, adiposity and fasting biochemistry (gl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2018-01-01
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| Series: | Journal of Nutritional Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2048679018000137/type/journal_article |
| _version_ | 1811155918587428864 |
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| author | Rona Antoni Tracey M. Robertson M. Denise Robertson Jonathan D. Johnston |
| author_facet | Rona Antoni Tracey M. Robertson M. Denise Robertson Jonathan D. Johnston |
| author_sort | Rona Antoni |
| collection | DOAJ |
| description | This pilot study explored the feasibility of a moderate time-restricted feeding (TRF) intervention and its effects on adiposity and metabolism. For 10 weeks, a free-living TRF group delayed breakfast and advanced dinner by 1·5 h each. Changes in dietary intake, adiposity and fasting biochemistry (glucose, insulin, lipids) were compared with controls who maintained habitual feeding patterns. Thirteen participants (29 (sem 2) kg/m2) completed the study. The average daily feeding interval was successfully reduced in the TRF group (743 (sem 32) to 517 (sem 22) min/d; P < 0·001; n 7), although questionnaire responses indicated that social eating/drinking opportunities were negatively impacted. TRF participants reduced total daily energy intake (P = 0·019) despite ad libitum food access, with accompanying reductions in adiposity (P = 0·047). There were significant between-group differences in fasting glucose (P = 0·008), albeit driven primarily by an increase among controls. Larger studies can now be designed/powered, based on these novel preliminary qualitative and quantitative data, to ascertain and maximise the long-term sustainability of TRF. |
| first_indexed | 2024-04-10T04:41:44Z |
| format | Article |
| id | doaj.art-61989636080f4c9b8304fb2ca259ad03 |
| institution | Directory Open Access Journal |
| issn | 2048-6790 |
| language | English |
| last_indexed | 2024-04-10T04:41:44Z |
| publishDate | 2018-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Nutritional Science |
| spelling | doaj.art-61989636080f4c9b8304fb2ca259ad032023-03-09T12:38:59ZengCambridge University PressJournal of Nutritional Science2048-67902018-01-01710.1017/jns.2018.13A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjectsRona Antoni0Tracey M. Robertson1M. Denise Robertson2Jonathan D. Johnston3Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UKFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UKFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UKFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UKThis pilot study explored the feasibility of a moderate time-restricted feeding (TRF) intervention and its effects on adiposity and metabolism. For 10 weeks, a free-living TRF group delayed breakfast and advanced dinner by 1·5 h each. Changes in dietary intake, adiposity and fasting biochemistry (glucose, insulin, lipids) were compared with controls who maintained habitual feeding patterns. Thirteen participants (29 (sem 2) kg/m2) completed the study. The average daily feeding interval was successfully reduced in the TRF group (743 (sem 32) to 517 (sem 22) min/d; P < 0·001; n 7), although questionnaire responses indicated that social eating/drinking opportunities were negatively impacted. TRF participants reduced total daily energy intake (P = 0·019) despite ad libitum food access, with accompanying reductions in adiposity (P = 0·047). There were significant between-group differences in fasting glucose (P = 0·008), albeit driven primarily by an increase among controls. Larger studies can now be designed/powered, based on these novel preliminary qualitative and quantitative data, to ascertain and maximise the long-term sustainability of TRF.https://www.cambridge.org/core/product/identifier/S2048679018000137/type/journal_articleChrononutritionCircadian rhythmsIntermittent fastingMetabolismFood intake |
| spellingShingle | Rona Antoni Tracey M. Robertson M. Denise Robertson Jonathan D. Johnston A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects Journal of Nutritional Science Chrononutrition Circadian rhythms Intermittent fasting Metabolism Food intake |
| title | A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects |
| title_full | A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects |
| title_fullStr | A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects |
| title_full_unstemmed | A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects |
| title_short | A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects |
| title_sort | pilot feasibility study exploring the effects of a moderate time restricted feeding intervention on energy intake adiposity and metabolic physiology in free living human subjects |
| topic | Chrononutrition Circadian rhythms Intermittent fasting Metabolism Food intake |
| url | https://www.cambridge.org/core/product/identifier/S2048679018000137/type/journal_article |
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