Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions

Hepatocellular carcinoma (HCC) can be diagnosed noninvasively on multiphasic CT and MRI based on its distinctive imaging findings. These features include arterial phase hyperenhancement and washout on portal or delayed phase images. However, radiologists face significant diagnostic challenges bec...

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Main Author: Jiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup Shim
Format: Article
Language:English
Published: The Korean Society of Radiology 2022-07-01
Series:대한영상의학회지
Online Access:https://doi.org/10.3348/jksr.2021.0178
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author Jiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup Shim
author_facet Jiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup Shim
author_sort Jiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup Shim
collection DOAJ
description Hepatocellular carcinoma (HCC) can be diagnosed noninvasively on multiphasic CT and MRI based on its distinctive imaging findings. These features include arterial phase hyperenhancement and washout on portal or delayed phase images. However, radiologists face significant diagnostic challenges because some HCCs exhibit atypical imaging characteristics. In addition to many HCC-mimicking lesions, such as arterioportal shunts, combined HCC-cholangiocarcinoma, intrahepatic cholangiocarcinoma, and hemangioma present a challenge for radiologists in actual clinical practice. The ability to distinguish HCCs from mimickers on initial imaging examinations is crucial for appropriate management and treatment decisions. Therefore, this pictorial review presents the imaging findings of atypical HCCs and HCCs mimicking malignant and benign lesions and discusses important clues that may help narrow down the differential diagnosis.
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spelling doaj.art-619995d2a708469ab2f0b5a7d82f88422022-12-22T01:33:10ZengThe Korean Society of Radiology대한영상의학회지2288-29282022-07-01834808829https://doi.org/10.3348/jksr.2021.0178Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking LesionsJiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup ShimHepatocellular carcinoma (HCC) can be diagnosed noninvasively on multiphasic CT and MRI based on its distinctive imaging findings. These features include arterial phase hyperenhancement and washout on portal or delayed phase images. However, radiologists face significant diagnostic challenges because some HCCs exhibit atypical imaging characteristics. In addition to many HCC-mimicking lesions, such as arterioportal shunts, combined HCC-cholangiocarcinoma, intrahepatic cholangiocarcinoma, and hemangioma present a challenge for radiologists in actual clinical practice. The ability to distinguish HCCs from mimickers on initial imaging examinations is crucial for appropriate management and treatment decisions. Therefore, this pictorial review presents the imaging findings of atypical HCCs and HCCs mimicking malignant and benign lesions and discusses important clues that may help narrow down the differential diagnosis.https://doi.org/10.3348/jksr.2021.0178
spellingShingle Jiyoung Yoon, So Hyun Park, Su Joa Ahn, Young Sup Shim
Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
대한영상의학회지
title Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
title_full Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
title_fullStr Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
title_full_unstemmed Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
title_short Atypical Manifestation of Primary Hepatocellular Carcinoma and Hepatic Malignancy Mimicking Lesions
title_sort atypical manifestation of primary hepatocellular carcinoma and hepatic malignancy mimicking lesions
url https://doi.org/10.3348/jksr.2021.0178
work_keys_str_mv AT jiyoungyoonsohyunparksujoaahnyoungsupshim atypicalmanifestationofprimaryhepatocellularcarcinomaandhepaticmalignancymimickinglesions