Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes

Abstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive pur...

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Main Author: Gianluca Franceschini
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Women's Health
Subjects:
Online Access:https://doi.org/10.1186/s12905-021-01436-9
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author Gianluca Franceschini
author_facet Gianluca Franceschini
author_sort Gianluca Franceschini
collection DOAJ
description Abstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive purpose in order to repair partial breast defects and improve aesthetic outcomes. However, some postoperative problems due to its use, such as allergic reactions, seroma, foreign-body reaction and misdiagnosis during the follow-up of breast cancer patients, have been shown. These possible surgical complications can undermine clinical outcomes and lead to delay the beginning of oncological treatments with a negative impact on patient quality of life and survival. An adequate surgical expertise and the compliance with some specific recommendations are crucial in order to minimize postoperative issues and optimise aesthetic outcomes.
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spelling doaj.art-6199bd4930a04f2c9a7c4f43050708032022-12-21T18:26:59ZengBMCBMC Women's Health1472-68742021-08-012111410.1186/s12905-021-01436-9Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomesGianluca Franceschini0Multidisciplinary Breast Unit, Department of Woman and Child Health and Public Health, Università Cattolica del Sacro CuoreAbstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive purpose in order to repair partial breast defects and improve aesthetic outcomes. However, some postoperative problems due to its use, such as allergic reactions, seroma, foreign-body reaction and misdiagnosis during the follow-up of breast cancer patients, have been shown. These possible surgical complications can undermine clinical outcomes and lead to delay the beginning of oncological treatments with a negative impact on patient quality of life and survival. An adequate surgical expertise and the compliance with some specific recommendations are crucial in order to minimize postoperative issues and optimise aesthetic outcomes.https://doi.org/10.1186/s12905-021-01436-9Breast cancerBreast conserving surgeryHemostatic materialsOxidized regenerated cellulosePostoperative complicationsAesthetic results
spellingShingle Gianluca Franceschini
Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
BMC Women's Health
Breast cancer
Breast conserving surgery
Hemostatic materials
Oxidized regenerated cellulose
Postoperative complications
Aesthetic results
title Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
title_full Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
title_fullStr Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
title_full_unstemmed Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
title_short Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
title_sort breast conserving surgery using oxidized regenerated cellulose as filling biomaterial recommendations to improve clinical outcomes
topic Breast cancer
Breast conserving surgery
Hemostatic materials
Oxidized regenerated cellulose
Postoperative complications
Aesthetic results
url https://doi.org/10.1186/s12905-021-01436-9
work_keys_str_mv AT gianlucafranceschini breastconservingsurgeryusingoxidizedregeneratedcelluloseasfillingbiomaterialrecommendationstoimproveclinicaloutcomes