Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes
Abstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive pur...
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Format: | Article |
Language: | English |
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BMC
2021-08-01
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Series: | BMC Women's Health |
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Online Access: | https://doi.org/10.1186/s12905-021-01436-9 |
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author | Gianluca Franceschini |
author_facet | Gianluca Franceschini |
author_sort | Gianluca Franceschini |
collection | DOAJ |
description | Abstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive purpose in order to repair partial breast defects and improve aesthetic outcomes. However, some postoperative problems due to its use, such as allergic reactions, seroma, foreign-body reaction and misdiagnosis during the follow-up of breast cancer patients, have been shown. These possible surgical complications can undermine clinical outcomes and lead to delay the beginning of oncological treatments with a negative impact on patient quality of life and survival. An adequate surgical expertise and the compliance with some specific recommendations are crucial in order to minimize postoperative issues and optimise aesthetic outcomes. |
first_indexed | 2024-12-22T11:51:28Z |
format | Article |
id | doaj.art-6199bd4930a04f2c9a7c4f4305070803 |
institution | Directory Open Access Journal |
issn | 1472-6874 |
language | English |
last_indexed | 2024-12-22T11:51:28Z |
publishDate | 2021-08-01 |
publisher | BMC |
record_format | Article |
series | BMC Women's Health |
spelling | doaj.art-6199bd4930a04f2c9a7c4f43050708032022-12-21T18:26:59ZengBMCBMC Women's Health1472-68742021-08-012111410.1186/s12905-021-01436-9Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomesGianluca Franceschini0Multidisciplinary Breast Unit, Department of Woman and Child Health and Public Health, Università Cattolica del Sacro CuoreAbstract Oxidized regenerated cellulose is considered an optimal local hemostatic agent thanks to its favorable biocompatibility, absorption characteristics and ease-of-use. Recently, oxidized regenerated cellulose has also been used as a filler in breast conserving surgery with a reconstructive purpose in order to repair partial breast defects and improve aesthetic outcomes. However, some postoperative problems due to its use, such as allergic reactions, seroma, foreign-body reaction and misdiagnosis during the follow-up of breast cancer patients, have been shown. These possible surgical complications can undermine clinical outcomes and lead to delay the beginning of oncological treatments with a negative impact on patient quality of life and survival. An adequate surgical expertise and the compliance with some specific recommendations are crucial in order to minimize postoperative issues and optimise aesthetic outcomes.https://doi.org/10.1186/s12905-021-01436-9Breast cancerBreast conserving surgeryHemostatic materialsOxidized regenerated cellulosePostoperative complicationsAesthetic results |
spellingShingle | Gianluca Franceschini Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes BMC Women's Health Breast cancer Breast conserving surgery Hemostatic materials Oxidized regenerated cellulose Postoperative complications Aesthetic results |
title | Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes |
title_full | Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes |
title_fullStr | Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes |
title_full_unstemmed | Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes |
title_short | Breast conserving surgery using oxidized regenerated cellulose as filling biomaterial: recommendations to improve clinical outcomes |
title_sort | breast conserving surgery using oxidized regenerated cellulose as filling biomaterial recommendations to improve clinical outcomes |
topic | Breast cancer Breast conserving surgery Hemostatic materials Oxidized regenerated cellulose Postoperative complications Aesthetic results |
url | https://doi.org/10.1186/s12905-021-01436-9 |
work_keys_str_mv | AT gianlucafranceschini breastconservingsurgeryusingoxidizedregeneratedcelluloseasfillingbiomaterialrecommendationstoimproveclinicaloutcomes |