Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review

Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline,...

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Main Authors: Jin Young Lee, Gil Ho Lee, Seung Hyun Yi, Woo Seog Sim, Bae Wook Kim, Hue Jung Park
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/8/2315
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author Jin Young Lee
Gil Ho Lee
Seung Hyun Yi
Woo Seog Sim
Bae Wook Kim
Hue Jung Park
author_facet Jin Young Lee
Gil Ho Lee
Seung Hyun Yi
Woo Seog Sim
Bae Wook Kim
Hue Jung Park
author_sort Jin Young Lee
collection DOAJ
description Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.
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spelling doaj.art-619c3f2020a544b3b2e8a155051b5f6d2023-11-19T00:21:59ZengMDPI AGBiomedicines2227-90592023-08-01118231510.3390/biomedicines11082315Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative ReviewJin Young Lee0Gil Ho Lee1Seung Hyun Yi2Woo Seog Sim3Bae Wook Kim4Hue Jung Park5Department of Anesthesiology and Pain Medicine, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaTrigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.https://www.mdpi.com/2227-9059/11/8/2315interventionpainpharmacotherapytreatmenttrigeminal neuralgia
spellingShingle Jin Young Lee
Gil Ho Lee
Seung Hyun Yi
Woo Seog Sim
Bae Wook Kim
Hue Jung Park
Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
Biomedicines
intervention
pain
pharmacotherapy
treatment
trigeminal neuralgia
title Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
title_full Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
title_fullStr Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
title_full_unstemmed Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
title_short Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review
title_sort non surgical treatments of trigeminal neuralgia from the perspective of a pain physician a narrative review
topic intervention
pain
pharmacotherapy
treatment
trigeminal neuralgia
url https://www.mdpi.com/2227-9059/11/8/2315
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