Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury
Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure. Antibiotics are one of the major causes of DILI. The authors report the case of a 37-year-ol...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2023-11-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/4119 |
| _version_ | 1797404178387042304 |
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| author | Carina Silva Susana Merim Rita Sevivas João Mota Alexandra Leitão |
| author_facet | Carina Silva Susana Merim Rita Sevivas João Mota Alexandra Leitão |
| author_sort | Carina Silva |
| collection | DOAJ |
| description | Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure. Antibiotics are one of the major causes of DILI. The authors report the case of a 37-year-old male with nausea, right hypochondrium pain and fever with history of bismuth subcitrate, metronidazole and tetracycline combination treatment in the previous five days. DILI was suspected and other aetiologies of acute hepatitis were excluded such as viral, autoimmune or even haemochromatosis and Wilson’s disease. Liver biopsy was performed, being compatible with the diagnosis of DILI; DILI is a diagnosis of exclusion. Bismuth subcitrate, metronidazole and tetracycline combination treatment is a rare cause of DILI. |
| first_indexed | 2024-03-09T02:51:11Z |
| format | Article |
| id | doaj.art-619c660d128d4a9b84fc1fe748301dcf |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-09T02:51:11Z |
| publishDate | 2023-11-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-619c660d128d4a9b84fc1fe748301dcf2023-12-05T10:10:16ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-11-0110.12890/2023_0041193654Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injuryCarina Silva0Susana Merim1Rita Sevivas2João Mota3Alexandra Leitão4Internal medicine department, Hospital Santa Maria Maior, Barcelos, PortugalInternal medicine department, Hospital Santa Maria Maior, Barcelos, PortugalInternal medicine department, Hospital Santa Maria Maior, Barcelos, PortugalInternal medicine department, Hospital Santa Maria Maior, Barcelos, PortugalInternal medicine department, Hospital Santa Maria Maior, Barcelos, PortugalDrug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure. Antibiotics are one of the major causes of DILI. The authors report the case of a 37-year-old male with nausea, right hypochondrium pain and fever with history of bismuth subcitrate, metronidazole and tetracycline combination treatment in the previous five days. DILI was suspected and other aetiologies of acute hepatitis were excluded such as viral, autoimmune or even haemochromatosis and Wilson’s disease. Liver biopsy was performed, being compatible with the diagnosis of DILI; DILI is a diagnosis of exclusion. Bismuth subcitrate, metronidazole and tetracycline combination treatment is a rare cause of DILI.https://www.ejcrim.com/index.php/EJCRIM/article/view/4119bismuth subcitratemetronidazoletetracyclinedrug-induced liver injury |
| spellingShingle | Carina Silva Susana Merim Rita Sevivas João Mota Alexandra Leitão Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury European Journal of Case Reports in Internal Medicine bismuth subcitrate metronidazole tetracycline drug-induced liver injury |
| title | Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury |
| title_full | Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury |
| title_fullStr | Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury |
| title_full_unstemmed | Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury |
| title_short | Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury |
| title_sort | bismuth subcitrate metronidazole and tetracycline a rare cause of drug induced liver injury |
| topic | bismuth subcitrate metronidazole tetracycline drug-induced liver injury |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/4119 |
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